Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lymphazurin
Drug ID BADD_D01334
Description Not Available
Indications and Usage Isosulfan Blue is a synthetic visual lymphatic imaging agent. Isosulfan blue upon subcutaneous administration, delineates the lymphatic vessels draining the region of injection. It is an adjunct to lymphography in: primary and secondary lymphedema of the extremities; chyluria, chylous ascites or chylothorax; lymph node involvement by primary or secondary neoplasm; lymph node response to therapeutic modalities.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB09136
KEGG ID D04634
MeSH ID C025484
PubChem ID 101316975
TTD Drug ID D0P2YD
NDC Product Code 14096-101; 59981-045; 69575-4004; 67457-220; 14501-0103; 68022-7525; 55150-240; 71288-805; 57821-003; 65862-911; 70069-221
UNII Not Available
Synonyms iso-sulfan blue | isosulfan blue | 4-(alpha-(p-(diethylamino)phenyl)-(2,5-disulfobenzylidene)-2,5-cyclohexadien-1-ylidene)diethylammonium hydroxide inner salt, sodium salt | iso-sulphan blue | Lymphazurin | lymphazurin blue
Chemical Information
Molecular Formula C27H32N2NaO6S2+
CAS Registry Number 748080-29-7
SMILES CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(=[N+](CC)CC)C=C2)C3=C(C=CC(=C3)S(=O)(=O)O)S(=O)(=O )[O-].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock10.01.07.002; 24.06.02.004---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Asthma10.01.03.010; 22.03.01.002---
Hypersensitivity10.01.03.003--
Pruritus23.03.12.001--
Respiratory distress22.02.01.012---
Shock24.06.02.002---
Urticaria10.01.06.001; 23.04.02.001--
Localised oedema02.05.04.006; 08.01.07.011; 14.05.06.009--
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