Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lormetazepam
Drug ID BADD_D01321
Description Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Indications and Usage For the treatment of short-term insomnia [L927]
Marketing Status approved
ATC Code N05CD06
DrugBank ID DB13872
KEGG ID D01657
MeSH ID C023842
PubChem ID 13314
TTD Drug ID D0I8HJ
NDC Product Code 12828-0021
UNII GU56C842ZA
Synonyms lormetazepam | methyllorazepam
Chemical Information
Molecular Formula C16H12Cl2N2O2
CAS Registry Number 848-75-9
SMILES CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O)C3=CC=CC=C3Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Gastrointestinal disorder07.11.01.001---
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperacusis04.02.02.001; 17.04.03.003---
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Immune system disorder10.02.01.001---
Irritability08.01.03.011; 19.04.02.013--
Libido decreased19.08.03.001; 21.03.02.005--
Micturition disorder20.02.02.005---
Muscular weakness15.05.06.001; 17.05.03.005--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001---
Nightmare19.02.03.003---
Paraesthesia17.02.06.005; 23.03.03.094--
Pruritus23.03.12.001--
Rash23.03.13.001---
Skin disorder23.03.03.007---
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder17.02.08.003; 19.19.02.002; 22.12.03.027---
Suicide attempt19.12.01.004--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Urethral disorder20.07.01.002---
Urinary tract disorder20.08.01.001---
Urticaria10.01.06.001; 23.04.02.001--
Visual impairment06.02.10.013---
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