Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Lorcaserin hydrochloride
Drug ID BADD_D01319
Description Lorcaserin (previously APD-356), a highly selective 5HT2C receptor agonist, is used for the treatment of obesity. It has been shown to reduce body weight and food intake in animal models of obesity, and it is thought that targeting the 5HT2C receptor may alter body weight by regulating satiety. Lorcaserin is marketed as a salt form called Belviq, which is lorcaserin hydrochloride.
Indications and Usage For the treatment of obesity, as an adjunct to a reduced-calorie diet and increased physical activity.
Marketing Status approved
ATC Code A08AA11
DrugBank ID DB04871
KEGG ID D06613
MeSH ID C506658
PubChem ID 11673085
TTD Drug ID D01JMC
NDC Product Code 14501-0023
UNII 0QJF08GDPE
Synonyms lorcaserin | (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine | Belviq | AR-10A | 8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine | APD 356 | APD356 | APD-356
Chemical Information
Molecular Formula C11H15Cl2N
CAS Registry Number 846589-98-8
SMILES CC1CNCCC2=C1C=C(C=C2)Cl.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vision blurred06.02.06.007; 17.17.01.010--
Visual impairment06.02.10.013---
Vomiting07.01.07.003--
Seasonal allergy06.04.01.013; 10.01.04.001; 22.04.04.008---
Cognitive disorder17.03.03.003; 19.21.02.001--
Angiopathy24.03.02.007---
Connective tissue disorder10.04.04.026; 15.06.01.006---
Infestation11.09.01.001; 23.11.01.002---
Inflammation08.01.05.007; 10.02.01.089---
Malnutrition14.03.02.004---
Mediastinal disorder22.09.03.001---
Mental disorder19.07.01.002---
Cardiac valve disease02.07.02.001---
Decreased appetite08.01.09.028; 14.03.01.005--
Regurgitation07.01.07.004---
Oropharyngeal pain07.05.05.004; 22.12.03.016--
The 3th Page    First    Pre   3    Total 3 Pages