Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Lithium carbonate
Drug ID BADD_D01303
Description Lithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Indications and Usage Lithium is used as a mood stabilizer, and is indicated for the treatment of manic episodes and maintenance of bipolar disorder[FDA Label].
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14509
KEGG ID D00801
MeSH ID D016651
PubChem ID 11125
TTD Drug ID D04UUH
NDC Product Code 31722-546; 62332-148; 62756-430; 63187-304; 64980-205; 68462-221; 70518-0608; 70518-2312; 70518-2345; 70518-3565; 72789-171; 72789-172; 31722-544; 62332-014; 68071-2714; 0054-8531; 46708-303; 55154-4920; 63629-1916; 0378-1450; 70518-0668; 70518-3681; 0054-4527; 62332-013; 68462-220; 68462-222; 68462-223; 70518-0437; 70518-2699; 68084-655; 70518-1434; 0054-2531; 71335-0120; 0054-8528; 0615-8302; 50090-3917; 58118-0545; 0054-8526; 51079-142; 63629-1917; 68462-224; 71610-557; 72789-173; 39345-5104; 46708-305; 0378-1300; 64980-278; 70518-1753; 70518-2086; 0054-2526; 31722-545; 50090-1470; 62332-015; 62559-280; 0054-0020; 68428-481; 0054-2527; 72789-174; 82388-001; 46708-148; 50090-6052; 64117-256; 0054-0021; 68084-640; 70518-0904; 70518-1481; 0054-8527; 66039-947; 73309-248; 23155-763; 42291-496; 43063-901; 46708-304; 51079-180
UNII 2BMD2GNA4V
Synonyms Lithium Carbonate | Carbonate, Lithium | Dilithium Carbonate | Carbonate, Dilithium | Lithane | Lithium Bicarbonate | Bicarbonate, Lithium | Lithobid | Lithonate | CP-15,467-61 | CP 15,467 61 | CP15,46761 | Micalith | NSC-16895 | NSC 16895 | NSC16895 | Priadel | Quilinorm-retard | Quilinorm retard | Quilinormretard | Eskalith | Lithotabs
Chemical Information
Molecular Formula CLi2O3
CAS Registry Number 554-13-2
SMILES [Li+].[Li+].C(=O)([O-])[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cognitive disorder17.03.03.003; 19.21.02.0010.001071%
Metabolic disorder14.11.01.0010.000803%-
Hyperexplexia03.10.01.003; 17.19.02.003---
Brugada syndrome02.03.02.033; 03.07.07.004---
Angiopathy24.03.02.007---
Urine output increased13.13.03.002---
Cardiac disorder02.11.01.003---
Electrocardiogram change13.14.05.014---
Malnutrition14.03.02.004---
Mental disorder19.07.01.0020.000535%-
Mental disorder due to a general medical condition19.07.03.005---
Poisoning12.03.01.004---
Abnormal behaviour19.01.01.0010.000803%-
Decreased appetite08.01.09.028; 14.03.01.0050.001874%
Erectile dysfunction19.08.04.001; 21.03.01.0070.000535%
Blood disorder01.05.01.0040.000535%-
Adverse drug reaction08.06.01.0090.003052%-
Disease recurrence08.01.03.0500.000803%-
Psychotic disorder19.03.01.0020.001071%
Renal impairment20.01.03.0100.004818%-
Joint hyperextension12.04.03.004; 15.01.08.003---
Chronic kidney disease20.01.03.0170.017400%
Bone marrow failure01.03.03.0050.000535%
Cardiovascular insufficiency02.11.01.011; 24.06.03.0050.000535%-
Substance abuse19.07.06.0180.000535%-
Renal cell carcinoma16.08.02.002; 20.01.04.0030.001338%-
Acute kidney injury20.01.03.0160.007870%
Toxicity to various agents12.03.01.046---
Posterior reversible encephalopathy syndrome17.13.02.0070.000803%
Drug reaction with eosinophilia and systemic symptoms10.01.01.021; 12.03.01.064; 23.03.05.0050.000803%-
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ADReCS-Target
Drug Name ADR Term Target
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