Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Levomefolate calcium
Drug ID BADD_D01277
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID Not Available
KEGG ID D09354
MeSH ID C569381
PubChem ID 135564391
TTD Drug ID Not Available
NDC Product Code 58159-062; 43615-002; 69723-002; 54239-008; 51927-5180; 80680-001
UNII A9R10K3F2F
Synonyms levomefolate calcium | N-(4-(((2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid calcium salt | safyral | metafolin
Chemical Information
Molecular Formula C20H23CaN7O6
CAS Registry Number 151533-22-1
SMILES CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001---
Abdominal pain07.01.05.002--
Breast pain21.05.05.003--
Breast tenderness21.05.05.004---
Cardiovascular disorder02.11.01.010; 24.03.02.009---
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chloasma18.08.02.002; 23.05.01.001---
Depressed mood19.15.02.001---
Depression19.15.01.001--
Embolism arterial24.01.01.014--
Embolism venous24.01.01.003---
Gallbladder disorder09.03.02.001---
Headache17.14.01.001--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Irritability08.01.03.011; 19.04.02.013--
Liver disorder09.01.08.001---
Migraine17.14.02.001; 24.03.05.003---
Mood altered19.04.02.007---
Myocardial infarction02.02.02.007; 24.04.04.009--
Nausea07.01.07.001--
Premenstrual syndrome17.14.01.019; 19.04.02.009; 21.01.01.007---
Pulmonary embolism22.06.02.001; 24.01.06.001---
Retinal vein occlusion06.10.01.010; 24.01.07.006---
Superior sagittal sinus thrombosis17.08.03.001; 24.01.04.004---
Tenderness08.01.08.005---
Uterine haemorrhage21.07.01.005; 24.07.03.004--
Uterine leiomyoma16.04.02.001; 21.07.02.004---
Vomiting07.01.07.003--
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