Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iron
Drug ID BADD_D01197
Description A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia.
Indications and Usage Used in preventing and treating iron-deficiency anemia.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB01592
KEGG ID Not Available
MeSH ID D007501
PubChem ID 23925
TTD Drug ID D0Y3TM
NDC Product Code 0220-2054; 62106-5042; 68428-383; 64117-791; 0220-2051; 0164-1152
UNII E1UOL152H7
Synonyms Iron | Iron-56 | Iron 56
Chemical Information
Molecular Formula Fe
CAS Registry Number 7439-89-6
SMILES [Fe]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Therapeutic reaction time decreased08.06.01.015---
Decreased appetite08.01.09.028; 14.03.01.0050.001904%
Feeling of body temperature change08.01.09.012---
Ill-defined disorder08.01.03.049---
Inner ear disorder04.04.02.002---
Polyp08.01.06.010; 16.02.02.005---
Sensation of foreign body08.01.09.002---
Blood disorder01.05.01.0040.000453%-
Drug intolerance08.06.01.013---
Sinus disorder22.04.06.0020.000907%
Poor quality sleep17.15.04.002; 19.02.05.005---
Bowel movement irregularity07.02.03.003---
Gastrointestinal inflammation07.08.03.0070.000453%-
Infusion site urticaria08.02.05.021; 10.01.06.010; 12.07.05.021; 23.04.02.010---
Iron overload12.02.08.005; 14.13.03.002--
Regurgitation07.01.07.004---
Gastrointestinal sounds abnormal07.01.01.002---
Oropharyngeal discomfort07.05.05.008; 22.12.03.015---
Oropharyngeal pain07.05.05.004; 22.12.03.016--
Acute kidney injury20.01.03.0160.000680%
Posterior reversible encephalopathy syndrome17.13.02.0070.000453%
Slow speech17.02.08.016; 19.19.02.004---
Faeces soft07.01.03.008---
Mouth swelling07.05.04.007; 10.01.05.020; 23.04.01.020---
Anal incontinence07.01.06.029; 17.05.01.021--
Normal newborn18.08.06.0010.000680%-
Rash papulosquamous23.03.08.0140.000453%-
Biliary dyskinesia09.03.02.0040.000453%-
Neurogenic shock17.02.10.025; 24.06.02.023---
Pharyngeal hypoaesthesia17.02.06.034; 22.04.05.017---
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