Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iothalamic acid
Drug ID BADD_D01184
Description Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Indications and Usage Conray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, endoscopic retrograde cholangiopancreatography, contrast enhancement of computed tomographic brain images, cranial computerized angiotomography, intravenous digital subtraction angiography and arterial digital subtraction angiography. Conray may also be used for enhancement of computed tomographic scans performed for detection and evaluation of lesions in the liver, pancreas, kidneys, abdominal aorta, mediastinum, abdominal cavity and retroperitoneal space.
Marketing Status approved
ATC Code V08AA04
DrugBank ID DB09133
KEGG ID D01258
MeSH ID D007483
PubChem ID 3737
TTD Drug ID D02KCV
NDC Product Code 52134-0503
UNII 16CHD79MIX
Synonyms Iothalamic Acid | Acid, Iothalamic | Methalamic Acid | Acid, Methalamic | Iotalamic Acid | Acid, Iotalamic | Conray 420 | Iodothalamate | Sodium Iothalamate | Iothalamate, Sodium | Iothalamic Acid, Monosodium Salt | Iothalamic Acid, Calcium (2:1) Salt | Iothalamic Acid, Monosilver (1+) Salt | Iothalamic Acid, Monosodium Salt, Dimer | Lopamidol | Angio-Conray | Angio Conray | AngioConray | Iothalamate
Chemical Information
Molecular Formula C11H9I3N2O4
CAS Registry Number 2276-90-6
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angina pectoris02.02.02.002; 24.04.04.002--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anuria20.01.03.002---
Aphasia17.02.03.001; 19.21.01.001--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001---
Asthma10.01.03.010; 22.03.01.002---
Body temperature increased13.15.01.001---
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.001--
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chills08.01.09.001; 15.05.03.016--
Choking22.12.03.003---
Coma17.02.09.001---
Cough22.02.03.001--
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.007--
Disseminated intravascular coagulation01.01.02.002; 24.01.01.010--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dry throat07.06.01.005; 22.12.03.005---
Dysphonia17.02.08.004; 19.19.03.002; 22.12.03.006--
Dyspnoea02.11.05.003; 22.02.01.004--
Ear disorder04.03.01.001---
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Erythema23.03.06.001---
Extravasation08.01.03.008---
Eye irritation06.04.05.003---
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