ADReCS

Pharmaceutical Information

Drug Name	Iohexol
Drug ID	BADD_D01180
Description	Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Indications and Usage	Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
Marketing Status	approved
ATC Code	V08AB02
DrugBank ID	DB01362
KEGG ID	D01817
MeSH ID	D007472
PubChem ID	3730
TTD Drug ID	D02BLO
NDC Product Code	43228-100; 0407-1413; 71806-141; 0407-1414; 0407-1416; 0407-1415; 0407-1401; 0407-1411; 0407-1412; 65072-0801; 54702-501
UNII	4419T9MX03
Synonyms	Iohexol \| Iohexol 350 \| Nycodenz \| Compound 545 \| Exypaque \| Omnipaque

Chemical Information

Molecular Formula	C19H26I3N3O9
CAS Registry Number	66108-95-0
SMILES	CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Petechiae	01.01.03.002; 23.06.01.003; 24.07.06.004	0.032010%		-
Pharyngeal oedema	10.01.05.016; 22.04.05.003; 23.04.01.016	0.179257%		-
Phlebitis	12.02.01.002; 24.12.03.004	0.007113%
Photophobia	06.01.01.004; 17.17.02.006	-	-
Pneumothorax	22.05.02.003	0.039124%
Posture abnormal	15.03.05.029; 17.02.05.033	0.007113%		-
Presyncope	02.11.04.013; 17.02.05.009; 24.06.02.010	0.041969%
Productive cough	22.02.03.005	0.014227%
Pruritus	23.03.12.001	3.294921%
Pulmonary oedema	02.05.02.003; 22.01.03.003	0.035567%
Pyrexia	08.05.02.003	0.315834%
Quadriplegia	17.01.04.013	-	-	-
Radiculopathy	17.10.01.005	-	-
Rales	22.12.01.011	0.007113%		-
Rash	23.03.13.001	0.899132%		-
Rash erythematous	23.03.13.029	0.153649%		-
Rash macular	23.03.13.003	0.059752%		-
Rash maculo-papular	23.03.13.004	0.067577%
Rash papular	23.03.13.017	0.017783%		-
Rash pruritic	23.03.13.030	0.100299%		-
Rash vesicular	23.03.13.009	0.010670%		-
Renal failure	20.01.03.005	-	-	-
Renal tubular necrosis	20.01.07.003	0.035567%		-
Respiration abnormal	22.02.01.041	0.007113%		-
Respiratory arrest	22.02.01.009	0.071134%		-
Respiratory disorder	22.02.07.002	0.088917%		-
Respiratory distress	22.02.01.012	0.125907%		-
Restlessness	17.02.05.021; 19.11.02.002	-	-
Retching	07.01.07.002	0.045526%		-
Rhinitis allergic	10.01.04.003; 22.04.04.003	0.007113%

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