Pharmaceutical Information |
Drug Name |
Iobenguane |
Drug ID |
BADD_D01172 |
Description |
Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008. |
Indications and Usage |
Detection of primary and metastatic pheochromocytoma or neuroblastoma |
Marketing Status |
approved; investigational |
ATC Code |
V09IX02 |
DrugBank ID |
DB06704
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KEGG ID |
Not Available
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MeSH ID |
D019797
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PubChem ID |
60860
|
TTD Drug ID |
Not Available
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NDC Product Code |
Not Available |
UNII |
35MRW7B4AD
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Synonyms |
3-Iodobenzylguanidine | 3 Iodobenzylguanidine | MIBG | meta-Iodobenzylguanidine | meta Iodobenzylguanidine | Iobenguane | m-Iodobenzylguanidine | m Iodobenzylguanidine | Iobenguane (131I) | 3-Iodobenzylguanidine, 125I Labeled | 125I Labeled 3-Iodobenzylguanidine | 3 Iodobenzylguanidine, 125I Labeled | (3-Iodo-(131I)benzyl)guanidine | 3-Iodobenzylguanidine, 123I Labeled | 123I Labeled 3-Iodobenzylguanidine | 3 Iodobenzylguanidine, 123I Labeled |
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Chemical Information |
Molecular Formula |
C8H10IN3 |
CAS Registry Number |
80663-95-2 |
SMILES |
C1=CC(=CC(=C1)I)CN=C(N)N |
Chemical Structure |
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ADRs Induced by Drug |
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