Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iobenguane
Drug ID BADD_D01172
Description Synthetic guanethidine derivative that locates phaeochromocytomas and neuroblastomas. The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline. Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Indications and Usage Detection of primary and metastatic pheochromocytoma or neuroblastoma
Marketing Status approved; investigational
ATC Code V09IX02
DrugBank ID DB06704
KEGG ID Not Available
MeSH ID D019797
PubChem ID 60860
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 35MRW7B4AD
Synonyms 3-Iodobenzylguanidine | 3 Iodobenzylguanidine | MIBG | meta-Iodobenzylguanidine | meta Iodobenzylguanidine | Iobenguane | m-Iodobenzylguanidine | m Iodobenzylguanidine | Iobenguane (131I) | 3-Iodobenzylguanidine, 125I Labeled | 125I Labeled 3-Iodobenzylguanidine | 3 Iodobenzylguanidine, 125I Labeled | (3-Iodo-(131I)benzyl)guanidine | 3-Iodobenzylguanidine, 123I Labeled | 123I Labeled 3-Iodobenzylguanidine | 3 Iodobenzylguanidine, 123I Labeled
Chemical Information
Molecular Formula C8H10IN3
CAS Registry Number 80663-95-2
SMILES C1=CC(=CC(=C1)I)CN=C(N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dermatitis23.03.04.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Haematoma24.07.01.001--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Injection site haemorrhage08.02.03.005; 12.07.03.005; 24.07.01.010---
Pruritus23.03.12.001--
Rash23.03.13.001---
Contusion12.01.06.001; 15.03.05.007; 23.03.11.002; 24.07.06.001--
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