Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Indinavir sulfate
Drug ID BADD_D01151
Description A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Indications and Usage Indinavir is an antiretroviral drug for the treatment of HIV infection.
Marketing Status Prescription; Discontinued
ATC Code J05AE02
DrugBank ID DB00224
KEGG ID D00897
MeSH ID D019469
PubChem ID 5462355
TTD Drug ID D0V7CF
NDC Product Code 0006-0573; 0006-0571
Synonyms Indinavir | MK-639 | MK 639 | MK639 | L-735 524 | L 735 524 | L735 524 | L-735,524 | L 735,524 | L735,524 | Crixivan | Indinavir Sulfate | Sulfate, Indinavir | Indinavir, Sulfate (1:1)
Chemical Information
Molecular Formula C36H49N5O8S
CAS Registry Number 157810-81-6
SMILES CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC= C5.OS(=O)(=O)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Amylase increased13.05.01.009--
Anaemia01.03.02.001--
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angina pectoris02.02.02.002; 24.04.04.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Bacteraemia11.01.11.001--
Blood bilirubin increased13.03.01.008--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Calculus urinary20.04.02.001--Not Available
Cardiovascular disorder02.01.01.001; 24.03.02.009--Not Available
Cerebrovascular disorder17.08.02.002; 24.03.05.002--Not Available
Cough22.02.03.001--
Crystalluria20.02.01.003--Not Available
Depression19.15.01.001--
Diabetes mellitus05.06.01.001; 14.06.01.001--Not Available
Diarrhoea07.02.01.001--
Dizziness02.01.02.004; 17.02.05.003; 24.06.02.007--
Dry skin23.03.03.001--
Dysgeusia07.14.03.001; 17.02.07.003--
Dyspepsia07.01.02.001--
Dyspnoea02.01.03.002; 22.02.01.004--
Dysuria20.02.02.002--
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