| Drug Name |
Immunoglobulin g (human) |
| Drug ID |
BADD_D01145 |
| Description |
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population. IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and 1.9% IgG4. IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. |
| Indications and Usage |
IVIg is used in the treatment of immunodeficiencies, as well as autoimmune and inflammatory disorders. These indications includes idiopathic thrombocytopenic purpura, Kawasaki disease, hypogammaglobulinemia, B cell chronic lymphocytic leukemia, bone marrow transplant complications, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy (CIDP), multiple sclerosis, rheumatoid arthritis, myesthenia gravis, Wiskott–Aldrich syndrome and inflammatory skin diseases. |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB00028
|
| KEGG ID |
Not Available
|
| MeSH ID |
D007074
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
44206-451; 44206-457; 69800-0250; 64208-8234; 44206-438; 64208-8235; 44206-454; 44206-452; 44206-456; 44206-436; 44206-437; 44206-439; 44206-455; 44206-458 |
| UNII |
Not Available
|
| Synonyms |
Immunoglobulin G | IgG | IgG Antibody | Antibody, IgG | Gamma Globulin, 7S | 7S Gamma Globulin | IgG2A | IgG2B | Polyglobin | Allerglobuline | IgG(T) | Immunoglobulin GT | GT, Immunoglobulin | IgG1 | IgG4 | IgG2 | IgG3 |
