Pharmaceutical Information |
Drug Name |
Imiquimod |
Drug ID |
BADD_D01142 |
Description |
Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. Imiquimod does not cure warts, and new warts may appear during treatment. Imiquimod does not fight the viruses that cause warts directly, however, it does help to relieve and control wart production. Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain types of skin cancer called superficial basal cell carcinoma. |
Indications and Usage |
For the topical treatment of clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adults. Also indicated for the treatment of external genital and perianal warts/condyloma acuminata in individuals 12 years old and above. |
Marketing Status |
approved; investigational |
ATC Code |
D06BB10 |
DrugBank ID |
DB00724
|
KEGG ID |
D02500
|
MeSH ID |
D000077271
|
PubChem ID |
57469
|
TTD Drug ID |
D06CTE
|
NDC Product Code |
62350-0077; 68682-272; 72189-084; 0168-0432; 22365-121; 51672-4174; 99207-271; 66039-829; 71052-160; 64552-4008; 45802-368; 51552-1538; 62147-0087; 51672-4145; 63629-8818; 68462-536; 51927-0168; 72643-006; 0093-3133; 99207-260; 99207-270; 99207-276; 58175-0397; 62147-0072 |
UNII |
P1QW714R7M
|
Synonyms |
Imiquimod | 1-Isobutyl-1H-imidazo(4,5-c)quinolin-4-amine | S 26308 | S-26308 | R 837 | R-837 | R837 | Zyclara | Aldara |
|
Chemical Information |
Molecular Formula |
C14H16N4 |
CAS Registry Number |
99011-02-6 |
SMILES |
CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N |
Chemical Structure |
|
|
ADRs Induced by Drug |
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
|
ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
Vulvovaginal inflammation | 21.14.02.014 | - | - | - |
|
|
|