Pharmaceutical Information |
Drug Name |
Imiglucerase |
Drug ID |
BADD_D01138 |
Description |
Human Beta-glucocerebrosidase or Beta-D-glucosyl-N-acylsphingosine glucohydrolase E.C. 3.2.1.45. 497 residue protein with N-linked carbohydrates, MW=59.3 kD. Alglucerase is prepared by modification of the oligosaccharide chains of human Beta-glucocerebrosidase. The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues. |
Indications and Usage |
For the treatment of Gaucher's disease (deficiency in glucocerebrosidase) |
Marketing Status |
approved |
ATC Code |
A16AB02 |
DrugBank ID |
DB00053
|
KEGG ID |
D03020
|
MeSH ID |
C090568
|
PubChem ID |
Not Available
|
TTD Drug ID |
D0QW9H
|
NDC Product Code |
67643-0020; 58468-4663 |
UNII |
Q6U6J48BWY
|
Synonyms |
imiglucerase | Cerezyme |
|
Chemical Information |
Molecular Formula |
Not Available |
CAS Registry Number |
154248-97-2 |
SMILES |
Not Available |
Chemical Structure |
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ADRs Induced by Drug |
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