| Pharmaceutical Information |
| Drug Name |
Ifosfamide |
| Drug ID |
BADD_D01133 |
| Description |
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent. |
| Indications and Usage |
Used as a component of various chemotherapeutic regimens as third-line therapy for recurrent or refractory germ cell testicular cancer. Also used as a component of various chemotherapeutic regimens for the treatment of cervical cancer, as well as in conjunction with surgery and/or radiation therapy in the treatment of various soft tissue sarcomas. Other indications include treatment of osteosarcoma, bladder cancer, ovarian cancer. small cell lung cancer, and non-Hodgkin's lymphoma. |
| Marketing Status |
approved |
| ATC Code |
L01AA06 |
| DrugBank ID |
DB01181
|
| KEGG ID |
D00343
|
| MeSH ID |
D007069
|
| PubChem ID |
3690
|
| TTD Drug ID |
D02TLO
|
| NDC Product Code |
10019-925; 57884-0006; 63323-142; 0143-9531; 0338-3991; 15308-0411; 0338-3993; 65124-0001; 0143-9530; 10019-926; 10019-927; 10019-929 |
| UNII |
UM20QQM95Y
|
| Synonyms |
Ifosfamide | Isofosfamide | Isophosphamide | Iphosphamide | Iso-Endoxan | Iso Endoxan | Holoxan | NSC-109,724 | NSC 109,724 | NSC109,724 | NSC-109724 | NSC 109724 | NSC109724 | Asta Z 4942 |
|
| Chemical Information |
| Molecular Formula |
C7H15Cl2N2O2P |
| CAS Registry Number |
3778-73-2 |
| SMILES |
C1CN(P(=O)(OC1)NCCCl)CCCl |
| Chemical Structure |
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| ADRs Induced by Drug |
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