| Drug Name |
Hydrocortisone sodium succinate |
| Drug ID |
BADD_D01091 |
| Description |
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.[A188420]
Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] |
| Indications and Usage |
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation.[L10529,L10532] Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions.[L10535] A hydrocortisone enema is indicated for ulcerative colitis,[L10538] a topical ointment with antibiotics is indicated for corticosteroid responsive dermatoses with infections,[L7772] and a topical cream with [acyclovir] is indicated to treat cold sores.[L7321] Oral granules of hydrocortisone are used as a replacement therapy for Adrenocortical Insufficiency (AI) in children under 17 years of age.[L16533] |
| Marketing Status |
approved; vet_approved |
| ATC Code |
S01CB03; H02AB09; S01BA02; C05AA01; D07AA02; A01AC03; D07XA01; S02BA01; A07EA02 |
| DrugBank ID |
DB00741
|
| KEGG ID |
D00978
|
| MeSH ID |
D006854
|
| PubChem ID |
23694214
|
| TTD Drug ID |
D0KR5B
|
| NDC Product Code |
22552-0007; 0009-0005; 0009-0013; 0009-0825; 0009-0016; 0009-0011; 64958-0020; 55154-3942 |
| UNII |
50LQB69S1Z
|
| Synonyms |
Hydrocortisone | Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)- | Cortisol | Cortef | Hydrocortisone, (11 alpha)-Isomer | Epicortisol | 11-Epicortisol | 11 Epicortisol | Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer | Cortifair | Cortril |
