Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydrocortisone cypionate
Drug ID BADD_D01089
Description Not Available
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
Marketing Status approved; investigational; vet_approved
ATC Code Not Available
DrugBank ID DB14541
KEGG ID D00976
MeSH ID C029109
PubChem ID 223253
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 4XDY25L70B
Synonyms hydrocortisone cypionate | hydrocortisone 21-cyclopentylpropionate
Chemical Information
Molecular Formula C29H42O6
CAS Registry Number 508-99-6
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)COC(=O)CCC5CCCC5)O)C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Alanine aminotransferase increased13.03.04.005--
Alkalosis hypokalaemic14.01.02.002---
Aspartate aminotransferase increased13.03.04.011--
Cardiac failure congestive02.05.01.002---
Cataract subcapsular06.06.01.002---
Cushingoid05.01.01.002; 14.11.01.006; 19.07.03.001; 24.08.02.004--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Erythema23.03.06.001---
Exophthalmos05.02.02.002; 06.09.04.001---
Fluid retention14.05.06.002; 20.01.02.003---
Glaucoma06.03.01.002--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypertension24.08.02.001--
Hypokalaemic syndrome14.05.03.003---
Hypothalamo-pituitary disorder05.03.04.003---
Impaired healing08.03.02.001---
Intracranial pressure increased17.07.02.002---
Intraocular pressure increased13.07.04.002---
Menstruation irregular05.05.01.008; 21.01.01.005--
Muscle disorder15.05.03.014---
Muscular weakness15.05.06.001; 17.05.03.005--
Myopathy15.05.05.001---
Nitrogen balance negative13.13.01.010---
Osteonecrosis15.02.04.007; 24.04.05.004--
Osteoporosis14.04.04.002; 15.02.03.002--
Pancreatitis07.18.01.001--
Papilloedema06.09.02.002; 17.07.02.004; 24.03.07.001--
Pathological fracture12.04.02.006; 15.08.02.008; 16.32.03.007---
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