| Drug Name |
Hydrocortisone |
| Drug ID |
BADD_D01086 |
| Description |
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex.[A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.[A188420]
Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] |
| Indications and Usage |
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation.[L10529,L10532] Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions.[L10535] A hydrocortisone enema is indicated for ulcerative colitis,[L10538] a topical ointment with antibiotics is indicated for corticosteroid responsive dermatoses with infections,[L7772] and a topical cream with [acyclovir] is indicated to treat cold sores.[L7321] Oral granules of hydrocortisone are used as a replacement therapy for Adrenocortical Insufficiency (AI) in children under 17 years of age.[L16533] |
| Marketing Status |
approved; vet_approved |
| ATC Code |
A01AC03; A07EA02; C05AA01; D07AA02; D07XA01; H02AB09; S01BA02; S01CB03; S02BA01 |
| DrugBank ID |
DB00741
|
| KEGG ID |
D00088
|
| MeSH ID |
D006854
|
| PubChem ID |
5754
|
| TTD Drug ID |
D0KR5B
|
| NDC Product Code |
76314-004; 38779-0009; 0904-7623; 51927-0143; 55718-159; 57582-013; 10356-120; 86014-200; 11673-057; 24286-1560; 30142-369; 0113-7006; 41167-0036; 41167-0331; 41167-0338; 41520-201; 0168-0146; 45334-327; 45802-276; 49035-973; 50090-5470; 51316-227; 51326-108; 51532-4608; 51672-2010; 51672-3004; 55910-646; 59088-209; 59256-004; 59779-878; 60687-582; 61010-5800; 63629-1952; 64980-301; 65923-035; 68062-9106; 68071-2818; 68788-8302; 0472-0321; 69842-155; 72189-276; 76348-585; 76348-804; 76420-028; 79481-0319; 37946-7520; 58624-0700; 11673-399; 11822-0471; 24385-276; 30142-541; 36800-524; 0115-1700; 41163-319; 41167-0342; 41167-0344; 42213-370; 43136-203; 43749-620; 45802-004; 49348-441; 50090-0350; 50090-5999; 50382-024; 51414-106; 55621-001; 55621-018; 55910-504; 62135-552; 63187-575; 63629-8667; 63736-339; 63868-689; 65923-393; 65923-925; 67234-010; 68016-099; 68016-102; 68071-1598; 69396-017; 70403-922; 71335-1989; 71399-0180; 72162-2018; 79481-0471; 79903-091; 0574-0420; 0904-7188; 49452-3580; 66406-0285; 68981-002; 11673-353; 21130-166; 24385-274; 0096-0732; 29784-142; 41163-471; 41163-973; 41167-0021; 41415-047; 0009-0044; 43136-103; 45802-014; 45802-937; 47682-397; 51822-021; 53002-9660; 53145-430; 53943-269; 53943-984; 58232-4010; 59088-268; 61269-345; 62135-551; 62172-203; 62282-504; 62559-138; 62559-430; 63187-543; 0363-1973; 63629-2529; 63629-8666; 63941-312; 65923-494; 67510-0065; 67510-0632; 68788-9922; 69315-312; 70518-3078; 70518-3275; 0573-0552; 71335-2044; 55301-201; 0316-0186; 0316-0193; 0316-0291; 59762-0073; 59762-0075; 61010-4402; 63629-2527; 63824-851; 63941-229; 0394-0859; 68071-2897; 68726-123; 68726-504; 69396-050; 69396-118; 69473-017; 69842-192; 70288-714; 71205-034; 72189-209; 76314-003; 79903-092; 55718-160; 58624-0703; 81918-001; 11673-398; 11822-2099; 36800-939; 0115-1696; 41167-0033; 41167-0039; 41167-0105; 41167-0108; 41167-0330; 41167-0336; 41250-887; 44911-0275; 45865-630; 0178-0455; 49035-732; 50268-407; 51414-107; 51824-050; 53002-8350; 53002-9662; 53329-091; 61269-343; 62011-0095; 62011-0096; 62135-020; 0363-0670; 63015-242; 63187-567; 64380-970; 65649-501; 68062-2264; 68071-2233; 68071-2261; 68391-100; 69396-028; 69396-055; 69842-292; 70000-0495; 71516-342; 72789-228; 37946-7518; 30142-411; 0113-1369; 36800-471; 36800-981; 41167-0032; 41167-0035; 41520-319; 42543-971; 42543-972; 0168-0015; 0168-0080; 43742-1275; 43749-250; 47682-211; 51672-2013; 53943-985; 55700-321; 55910-541; 59651-415; 59762-0074; 61269-339; 63187-504; 63868-955; 68016-063; 68071-5205; 68788-8455; 69396-005; 69968-0511; 76314-002; 79481-0973; 79503-202; 0924-5633; 60722-1001; 21130-395; 24385-021; 0113-0471; 0113-0541; 0113-0973; 0115-1697; 37808-973; 41167-0335; 41250-369; 0168-0020; 44577-623; 50090-0527; 55315-182; 59779-729; 62135-186; 62742-4077; 63187-480; 63629-8668; 63629-9057; 63736-029; 64380-971; 65649-401; 67091-419; 68016-909; 68062-9103; 68788-8078; 0472-0337; 69103-4506; 69396-081; 69729-269; 71101-800; 71399-0120; 73408-933; 73408-981; 76420-110; 0009-0069; 22552-0037; 37946-6503; 51927-0144; 10107-429; 59929-107; 64025-0001; 64958-0008; 64958-0096; 66406-0050; 71216-3006; 82298-101; 11527-052; 11673-202; 11673-842; 24385-190; 30142-973; 36800-018; 36800-059; 37808-319; 37808-471; 41167-0028; 41520-033; 42543-970; 47682-398; 49035-707; 49967-108; 51316-230; 51672-3003; 52410-3050; 55315-181; 0316-0128; 62559-431 |
| UNII |
WI4X0X7BPJ
|
| Synonyms |
Hydrocortisone | Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)- | Cortisol | Cortef | Hydrocortisone, (11 alpha)-Isomer | Epicortisol | 11-Epicortisol | 11 Epicortisol | Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer | Cortifair | Cortril |
