| Drug Name |
Homatropine hydrobromide |
| Drug ID |
BADD_D01076 |
| Description |
Homatropine is an anticholinergic drug that acts as an antagonist at muscarinic acetylcholine receptors. It is present in antitussives, under the trade name Hycodan, in combination with hydrocodone (dihydrocodeinone) bitartrate indicated for the symptomatic relief of cough as oral tablets or solutions. Homatropine is included in subtherapeutic amounts as homatropine methylbromide to discourage deliberate overdosage. Homatropine hydrobromide has been administered as ophthalmic solutions as a cycloplegic to temporarily paralyze accomodation, and to induce mydriasis (the dilation of the pupil); however such therapeutic use has not been approved by the FDA to be safe and effective. |
| Indications and Usage |
Indicated as an overdose-rescuing agent in combination with hydrocodone antitussive [FDA Label].
Indicated for the induction of mydriasis in ophthalmic solutions. |
| Marketing Status |
approved |
| ATC Code |
S01FA05 |
| DrugBank ID |
DB11181
|
| KEGG ID |
D01004
|
| MeSH ID |
C100236
|
| PubChem ID |
6419941
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
69205-039; 59390-192; 69205-749; 62068-375; 42385-749 |
| UNII |
BEW7469QZ0
|
| Synonyms |
homatropine | homatropine, (3(S)-endo)-isomer | homatropine, exo-(+-)-isomer | I - Homatrine | Isopto Homatropine | Minims-Homatropin | AK-Homatropine | Homatropin - POS | homatropine hydrobromide, (endo-(+-)-isomer) | homatropine hydrochloride, (endo-(+-)-isomer) | homatropine sulfate (1:1), (3(R)-endo)-isomer | homatropine sulfate (1:1), (3(S)-endo)-isomer | homatropine sulfate (2:1), endo-isomer | Minims-Homatropine Hydrobromide |
