Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol propionate
Drug ID BADD_D01052
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status Prescription; Discontinued
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D04409
MeSH ID C064466
PubChem ID 48175
TTD Drug ID D00XPC
NDC Product Code 0713-0758; 64918-1206; 51862-606; 52128-138; 45802-129; 63629-8735; 0713-0339; 70752-119; 51672-1321; 51862-604; 10631-122; 45802-131; 58175-0391; 0713-0640; 0187-0002; 52565-073; 63629-8665; 22552-0001; 63739-998; 0168-0355; 50909-5157; 46204-0188; 63629-8664; 51672-1322
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C25H31ClF2O5
CAS Registry Number 66852-54-8
SMILES CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)CCl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001--Not Available
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004--Not Available
Dry skin23.03.03.001--
Erythema23.03.06.001--Not Available
Folliculitis11.01.12.018; 23.09.04.007--
Hypertrichosis23.02.04.002--
Infection11.01.08.002--Not Available
Leukoderma23.05.02.001--Not Available
Miliaria23.02.03.014--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash pustular11.01.12.002; 23.03.10.003--
Skin atrophy23.01.05.001--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002--Not Available
Telangiectasia23.06.03.001; 24.03.03.003--
Urticaria10.01.06.001; 23.04.02.001--
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