Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Halobetasol propionate
Drug ID BADD_D01052
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage Ulobetasol cream and ointment are indicated in the treatment of inflammatory and pruritic corticosteroid responsive dermatoses.[L15047] Ulobetasol lotion is indicated in the treatment of plaque psoriasis.[L15052]
Marketing Status approved
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D04409
MeSH ID C064466
PubChem ID 48175
TTD Drug ID D00XPC
NDC Product Code 22552-0001; 63629-8665; 0713-0640; 58175-0391; 63629-8664; 46204-0188; 45802-129; 45802-131; 0187-0002; 70752-119; 10631-122; 0713-0339; 51672-1322; 51862-606; 63629-8735; 0713-0758; 52128-138; 51672-1321; 51862-604; 64918-1206; 0168-0355; 50909-5157
UNII 91A0K1TY3Z
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C25H31ClF2O5
CAS Registry Number 66852-54-8
SMILES CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)CCl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.001---
Burning sensation08.01.09.029; 17.02.06.001---
Dermatitis23.03.04.002---
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004---
Dry skin23.03.03.001--
Erythema23.03.06.001---
Folliculitis11.02.01.053; 23.11.04.003--
Hypertrichosis23.02.04.002--
Infection11.01.08.002---
Leukoderma23.05.02.001---
Miliaria23.02.03.014---
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Pruritus23.03.12.001--
Rash23.03.13.001---
Rash pustular11.01.12.002; 23.03.10.003--
Skin atrophy23.01.05.001--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002---
Telangiectasia23.06.03.001; 24.03.03.003--
Urticaria10.01.06.001; 23.04.02.001--
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