Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halcinonide
Drug ID BADD_D01050
Description Halcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc. Research suggests that clobetasol propionate demonstrates superior pharmacologic efficacy in the treatment of psoriasis when compared to halcinonide.
Indications and Usage Indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Marketing Status approved; investigational; withdrawn
ATC Code D07AD02
DrugBank ID DB06786
KEGG ID D01308
MeSH ID D006206
PubChem ID 443943
TTD Drug ID D06IIB
NDC Product Code 10631-096; 71428-011; 0378-8056; 0003-0249; 46439-8717; 57664-698
UNII SI86V6QNEG
Synonyms Halcinonide | Alcinonide | Halciderm | Halcimat | Halog | Dermalog | SQ-18,566 | SQ 18,566 | SQ18,566
Chemical Information
Molecular Formula C24H32ClFO5
CAS Registry Number 3093-35-4
SMILES CC1(OC2CC3C4CCC5=CC(=O)CCC5(C4(C(CC3(C2(O1)C(=O)CCl)C)O)F)C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Atrophy08.03.04.001---
Burning sensation08.01.09.029; 17.02.06.001---
Cataract subcapsular06.06.01.002---
Dermatitis23.03.04.002---
Dermatitis acneiform23.02.01.004--
Dermatitis contact10.01.01.003; 12.03.01.040; 23.03.04.004---
Dermatitis infected11.01.12.011; 23.03.04.024---
Dry skin23.03.03.001--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002---
Erythema23.03.06.001---
Folliculitis11.02.01.053; 23.11.04.003--
Hirsutism05.05.01.005; 23.02.04.001--
Hypertension24.08.02.001--
Hypertrichosis23.02.04.002--
Infection11.01.08.002---
Leukoderma23.05.02.001---
Miliaria23.02.03.014---
Muscular weakness15.05.06.001; 17.05.03.005--
Oedema08.01.07.006; 14.05.06.010---
Peptic ulcer07.04.07.001---
Pruritus23.03.12.001--
Pyoderma11.01.12.009; 23.11.02.016---
Secondary adrenocortical insufficiency05.03.04.012; 14.11.01.014---
Skin atrophy23.01.05.001--
Skin hypopigmentation23.05.02.003--
Skin irritation23.03.04.009---
Skin striae23.01.05.002---
Swelling08.01.03.015---
Skin maceration23.03.03.016---
Pigmentation disorder23.05.03.001---
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