| Pharmaceutical Information |
| Drug Name |
Gonadorelin |
| Drug ID |
BADD_D01036 |
| Description |
Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pituitary. |
| Indications and Usage |
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation. |
| Marketing Status |
approved; investigational; vet_approved |
| ATC Code |
H01CA01; V04CM01 |
| DrugBank ID |
DB00644
|
| KEGG ID |
D08027
|
| MeSH ID |
D007987
|
| PubChem ID |
638793
|
| TTD Drug ID |
D04ODH
|
| NDC Product Code |
55463-0016 |
| UNII |
9O7312W37G
|
| Synonyms |
Gonadotropin-Releasing Hormone | Gonadotropin Releasing Hormone | Gn-RH | Gonadoliberin | LHFSH Releasing Hormone | Releasing Hormone, LHFSH | LH-RH | LFRH | LH-Releasing Hormone | LH Releasing Hormone | LH-FSH Releasing Hormone | LH FSH Releasing Hormone | LHFSHRH | LHRH | Luliberin | Gonadorelin | Luteinizing Hormone-Releasing Hormone | Luteinizing Hormone Releasing Hormone | FSH-Releasing Hormone | FSH Releasing Hormone | GnRH | Factrel | Cystorelin | Gonadorelin Hydrochloride | Kryptocur | Dirigestran | Gonadorelin Acetate |
|
| Chemical Information |
| Molecular Formula |
C55H75N17O13 |
| CAS Registry Number |
9034-40-6 |
| SMILES |
CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C
2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6 |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
|
|
|
