Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Glutamine
Drug ID BADD_D01029
Description A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells. An oral formulation of L-glutamine was approved by the FDA in July 2017 for use in sickle cell disease [L892]. This oral formulation is marketed under the tradename Endari by Emmaus Medical.
Indications and Usage Used for nutritional supplementation, also for treating dietary shortage or imbalance. Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older [FDA Label].
Marketing Status approved; investigational; nutraceutical
ATC Code A16AA03
DrugBank ID DB00130
KEGG ID D00015
MeSH ID D005973
PubChem ID 5961
TTD Drug ID D01JIA
NDC Product Code 58159-080; 42457-420; 51552-0285
UNII 0RH81L854J
Synonyms Glutamine | L-Glutamine | L Glutamine | D-Glutamine | D Glutamine
Chemical Information
Molecular Formula C5H10N2O3
CAS Registry Number 56-85-9
SMILES C(CC(=O)N)C(C(=O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Sickle cell anaemia with crisis01.04.02.0010.017249%-
Skin disorder23.03.03.007---
Thirst08.01.09.021; 14.03.02.007---
Urethral disorder20.07.01.002---
Urinary tract disorder20.08.01.001---
Viral infection11.05.04.001---
Vomiting07.01.07.003--
Musculoskeletal discomfort15.03.04.001---
Rectal tenesmus07.03.03.001; 15.05.03.011---
Angiopathy24.03.02.007---
Bacterial infection11.02.01.005---
Malnutrition14.03.02.004---
Mental disorder19.07.01.002---
Ill-defined disorder08.01.03.049---
Adverse drug reaction08.06.01.0090.004312%-
Anorectal discomfort07.03.03.003---
Candida infection11.03.03.021--
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ADReCS-Target
Drug Name ADR Term Target
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