| Drug Name |
Gemeprost |
| Drug ID |
BADD_D01011 |
| Description |
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy [A19726]. It is not FDA-approved but available in Japan marketed as Preglandin. |
| Indications and Usage |
Indicated for the softening and dilatation of the cervix uteri prior to transcervical, intrauterine operative procedures in the first trimester of pregnancy or facilitating therapeutic termination of pregnancy in patients in the second trimester of gestation. |
| Marketing Status |
approved; withdrawn |
| ATC Code |
G02AD03 |
| DrugBank ID |
DB08964
|
| KEGG ID |
D02073
|
| MeSH ID |
C021182
|
| PubChem ID |
5282237
|
| TTD Drug ID |
D0EC5X
|
| NDC Product Code |
Not Available |
| UNII |
45KZB1FOLS
|
| Synonyms |
gemeprost | 16,16-dimethyl-delta(2)-PGE1 methyl ester | Preglandin | 16,16-DMTDPGEME | 16,16-dimethyl-delta(2)-prostaglandin E1 methyl ester | Cervagem | Cervagème | gemeprost, (2E,11alpha,13E,15R)-isomer | PG802 | Cergem | 16,16-dimethyl-trans-delta(2)-PGE(1) methyl ester | 16,16-dimethyl-trans-delta(2)-prostaglandin E(1) methyl ester | ONO 802 | ONO-802 |
