| Drug Name |
Formoterol |
| Drug ID |
BADD_D00958 |
| Description |
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001.[L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers.[A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration of action (12 hours) - for this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication.[L11256] It is available as a single-entity product[L10986,L11223] and in several formulations in combination with both inhaled corticosteroids[L10995,L10619] and long-acting muscarinic antagonists.[L10992,L10989] |
| Indications and Usage |
Formoterol is indicated in various formulations for the treatment of asthma and COPD. For the treatment of COPD, formoterol is available as a single-entity inhalation solution,[L10986] in combination with the long-acting muscarinic antagonists (LAMAs) [aclidinium][L10992] and [glycopyrronium],[L10989] and in combination with the corticosteroid [budesonide].[L10619] For the treatment of asthma, formoterol is available in combination with [mometasone furoate] for patients 5 years and older[L10995] and with budesonide for patients 6 years and older.[L10619] Formoterol may also be used on an as-needed basis for prophylaxis against exercise-induced bronchospasm.[L10998] |
| Marketing Status |
approved; investigational |
| ATC Code |
R03AC13; R03CC15 |
| DrugBank ID |
DB00983
|
| KEGG ID |
D07990
|
| MeSH ID |
D000068759
|
| PubChem ID |
3410
|
| TTD Drug ID |
D04KJO
|
| NDC Product Code |
Not Available |
| UNII |
5ZZ84GCW8B
|
| Synonyms |
Formoterol Fumarate | Formoterol Fumarate, ((R*,R*)-(+-))-isomer | 3-Formylamino-4-hydroxy-alpha-(N-1-methyl-2-p-methoxyphenethylaminomethyl)benzyl alcohol.hemifumarate | BD 40A | Formoterol | Eformoterol | Oxis | Arformoterol | Formoterol, ((R*,R*)-(+-))-isomer | Foradil |
