Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fluphenazine hydrochloride
Drug ID BADD_D00937
Description A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Indications and Usage For management of manifestations of psychotic disorders.
Marketing Status approved
ATC Code N05AB02
DrugBank ID DB00623
KEGG ID D00791
MeSH ID D005476
PubChem ID 67356
TTD Drug ID D0P5SA
NDC Product Code 0832-6005; 10135-728; 68022-7063; 16714-675; 50268-368; 51672-4233; 70518-1496; 70771-1581; 71205-839; 48954-468; 69766-068; 51672-4235; 63323-281; 70954-275; 0832-6003; 46204-0002; 16714-672; 24979-137; 24979-138; 27241-254; 50268-366; 60505-4770; 62135-415; 70518-3095; 70710-1489; 70771-1583; 70954-273; 62135-418; 69238-1678; 69238-1679; 70710-1491; 70954-274; 71205-838; 71205-840; 16714-674; 24979-136; 27241-253; 43598-034; 43598-036; 43826-041; 51407-461; 51672-4234; 0527-1789; 0527-1791; 70518-3553; 71554-027; 0121-0653; 42291-438; 43826-038; 62135-416; 62135-419; 0527-1788; 70518-3707; 70771-1582; 0904-7158; 10135-726; 43598-035; 50268-369; 60505-4771; 68084-846; 68084-950; 69238-1680; 70954-276; 71205-837; 76055-0044; 0121-0654; 42291-435; 51407-458; 51672-4236; 60505-4768; 70518-3098; 70518-3569; 70710-1488; 0832-6004; 0832-6006; 0904-7157; 0904-7159; 0904-7160; 16714-673; 24979-139; 51407-460; 60505-4769; 70771-1584; 10135-725; 27241-252; 50268-367; 69238-1681; 0527-1790; 70710-1490; 10135-727; 27241-255; 42291-436; 42291-437; 43598-037; 43826-039; 43826-040; 51407-459
UNII ZOU145W1XL
Synonyms Fluphenazine | Flufenazin | Fluphenazine Hydrochloride | Hydrochloride, Fluphenazine | Lyogen | Prolixin
Chemical Information
Molecular Formula C22H28Cl2F3N3OS
CAS Registry Number 146-56-5
SMILES C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Leukopenia01.02.02.001---
Libido increased19.08.03.002; 21.03.02.007--
Mastication disorder07.01.06.016; 15.03.05.022; 17.05.03.006---
Menstruation irregular05.05.01.008; 21.01.01.005--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Neurogenic bladder17.10.01.002; 20.03.03.001---
Neuroleptic malignant syndrome08.05.01.005; 12.03.01.003; 15.05.04.015; 17.05.02.003---
Oculogyric crisis06.05.02.002; 17.01.03.002---
Oedema peripheral02.05.04.007; 08.01.07.007; 14.05.06.011--
Opisthotonus17.01.03.005---
Pancytopenia01.03.03.003---
Parkinsonism17.01.05.003---
Photosensitivity reaction23.03.09.003--
Polyuria20.02.03.002---
Pregnancy test false positive13.10.05.003---
Protrusion tongue07.14.02.002; 17.02.05.037---
Pruritus23.03.12.001--
Restlessness17.02.05.021; 19.11.02.002--
Salivary hypersecretion07.06.01.009---
Seborrhoea23.02.07.001---
Somnolence17.02.04.006; 19.02.05.003--
Swelling08.01.03.015---
Systemic lupus erythematosus10.04.03.004; 15.06.02.003; 23.03.02.006---
Tachycardia02.03.02.007---
Thrombocytopenia01.08.01.002---
Urticaria10.01.06.001; 23.04.02.001--
Vision blurred06.02.06.007; 17.17.01.010--
Brain oedema12.01.10.010; 17.07.02.003--
Analgesic therapy25.01.04.001---
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