Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluphenazine
Drug ID BADD_D00935
Description A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Indications and Usage For management of manifestations of psychotic disorders.
Marketing Status approved
ATC Code N05AB02
DrugBank ID DB00623
KEGG ID D07977
MeSH ID D005476
PubChem ID 3372
TTD Drug ID D0P5SA
NDC Product Code Not Available
UNII S79426A41Z
Synonyms Fluphenazine | Flufenazin | Fluphenazine Hydrochloride | Hydrochloride, Fluphenazine | Lyogen | Prolixin
Chemical Information
Molecular Formula C22H26F3N3OS
CAS Registry Number 69-23-8
SMILES C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Glaucoma06.03.01.002--
Gynaecomastia05.05.02.003; 21.05.04.003--
Headache17.14.01.001--
Hepatocellular injury09.01.07.008---
Hyperkinesia17.01.02.008---
Hyperreflexia17.02.01.002---
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertonia15.05.04.007; 17.05.02.001---
Hypokinesia17.01.02.009---
Hypotension24.06.03.002--
Hypotonia15.05.04.008; 17.05.02.002---
Ileus paralytic07.02.05.001---
Insomnia17.15.03.002; 19.02.01.002--
Irritability08.01.03.011; 19.04.02.013--
Jaundice cholestatic09.01.01.005---
Laryngeal oedema10.01.05.003; 22.04.02.001; 23.04.01.005--
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
Leukocytosis01.02.01.002--
Leukopenia01.02.02.001---
Libido increased19.08.03.002; 21.03.02.007--
Menstruation irregular05.05.01.008; 21.01.01.005--
Mitral valve incompetence02.07.01.002---
Muscle rigidity15.05.04.001; 17.05.02.005---
Muscle spasms15.05.03.004--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Neurogenic bladder17.10.01.002; 20.03.03.001---
Neuroleptic malignant syndrome08.05.01.005; 12.03.01.003; 15.05.04.015; 17.05.02.003---
Oculogyric crisis06.05.02.002; 17.01.03.002---
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ADReCS-Target
Drug Name ADR Term Target
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