| Drug Name |
Fluocinolone acetonide |
| Drug ID |
BADD_D00924 |
| Description |
Fluocinolone acetonide, with the formula 6-alpha, 9-alpha-difluoro-16-alpha, 17 alpha-acetonide, is a corticosteroid that presents a high lipophilicity.[T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676] |
| Indications and Usage |
Fluocinolone acetonide has been used extensively in different medical areas.
-In dermatology, it is extensively used for the relief of inflammatory dermatosis, dermatitis, psoriasis, hypertrophic tissues, keloid tissues and atopic dermatitis.[F1955]
-It has been used in shampoo products as a low to medium potency corticosteroid for the treatment of seborrheic dermatitis of the scalp.[L4682]
-In ear drops, it is used as a low to medium potency corticosteroid for the treatment of chronic eczematous external otitis in adults and pediatric patients 2 years and older.[L4683]
-As an intravitreal implant, it is indicated for the treatment of diabetic macular edema with patients that have been previously treated with a course of corticosteroids and no clinically significant rise in intraocular pressure.[L4684]
-Fluocinolone acetonide was announced on October 15, 2018 to be FDA approved for the treatment of chronic non-infectious uveitis affecting the posterior segment of the eye.[L4685]
-Some reports have indicated the use of fluocinolone acetonide as a vasoprotective agent and for its use in the treatment of first-degree hemorrhoids.[A39532] |
| Marketing Status |
approved; investigational; vet_approved |
| ATC Code |
C05AA10; D07AC04; S01BA15; S02BA08 |
| DrugBank ID |
DB00591
|
| KEGG ID |
D01825
|
| MeSH ID |
D005446
|
| PubChem ID |
6215
|
| TTD Drug ID |
D02QJH
|
| NDC Product Code |
43538-910; 45802-485; 51672-1357; 51672-1365; 64980-331; 53183-0261; 71161-134; 65162-704; 68462-185; 0713-0224; 76420-163; 39328-079; 43538-900; 45802-009; 71879-136; 68611-190; 71428-002; 0713-0223; 0395-8243; 24208-416; 63629-8655; 70752-156; 38779-0022; 51927-0150; 10135-670; 43386-069; 43538-901; 43538-920; 51672-1356; 68462-590; 68791-103; 46439-8709; 0299-5500; 64980-330; 65162-702; 70752-158; 49452-3156; 0168-0064; 63629-8656; 68462-591; 68791-102; 65162-703; 70752-159; 0713-0709; 68791-101; 43538-911; 43538-921; 45802-887 |
| UNII |
0CD5FD6S2M
|
| Synonyms |
Fluocinolone Acetonide | Acetonide, Fluocinolone | Fluortriamcinolone Acetonide | Acetonide, Fluortriamcinolone | Flurosyn | Jellin | Jellisoft | Synalar | Synalar-HP | Synalar HP | Synemol | Synamol | Alvadermo | Capex | Co-Fluocin | Co Fluocin | Cortiespec | Derma-Smooth FS | Derma Smooth FS | Flucinar | Fluocid | Fluodermo | Fluonid | Fluotrex | Flusolgen | Gelidina |
