Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Flunitrazepam
Drug ID BADD_D00922
Description Flunitrazepam is a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
Indications and Usage For short-term treatment of severe insomnias, that are not responsive to other hypnotics.
Marketing Status approved; illicit
ATC Code N05CD03
DrugBank ID DB01544
KEGG ID D01230
MeSH ID D005445
PubChem ID 3380
TTD Drug ID D0W2NM
NDC Product Code Not Available
UNII 620X0222FQ
Synonyms Flunitrazepam | Fluridrazepam | Flunibeta | Flunimerck | Fluninoc | Rohypnol | Rohipnol | Narcozep | Flunitrazepam-Ratiopharm | Flunitrazepam Ratiopharm | Flunitrazepam-Teva | Flunitrazepam Teva | Flunizep Von Ct | Von Ct, Flunizep | RO-5-4200 | RO54200 | Fluni 1A Pharma | Flunitrazepam-Neuraxpharm | Flunitrazepam Neuraxpharm
Chemical Information
Molecular Formula C16H12FN3O3
CAS Registry Number 1622-62-4
SMILES CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Aggression19.05.01.001---
Agitation17.02.05.012; 19.06.02.001--
Amnesia17.03.02.001; 19.20.01.001--
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Anxiety19.06.02.002--
Asthenia08.01.01.001---
Ataxia08.01.02.004; 17.02.02.001--
Confusional state17.02.03.005; 19.13.01.001--
Delusion19.10.01.001--
Dermatitis23.03.04.002---
Diplopia06.02.06.002; 17.17.01.005---
Discomfort08.01.08.003---
Disorientation17.02.05.015; 19.13.01.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dry mouth07.06.01.002--
Dysarthria17.02.08.001; 19.19.03.001--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Hallucination19.10.04.003--
Hangover08.01.09.018---
Headache17.14.01.001--
Hiccups07.01.06.009; 22.12.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypotension24.06.03.002--
Irritability08.01.03.011; 19.04.02.013--
Malaise08.01.01.003--
Muscular weakness15.05.06.001; 17.05.03.005--
Nightmare19.02.03.003---
Orthostatic hypotension17.05.01.020; 24.06.03.004---
Rash23.03.13.001---
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