Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Flucytosine
Drug ID BADD_D00913
Description A fluorinated cytosine analog that is used as an antifungal agent.
Indications and Usage For the treatment (in combination with amphotericin B) of serious infections caused by susceptible strains of Candida (septicemia, endocarditis and urinary system infections) and/or Cryptococcus (meningitis and pulmonary infections).
Marketing Status Prescription
ATC Code D01AE21; J02AX01
DrugBank ID DB01099
KEGG ID D00323
MeSH ID D005437
PubChem ID 3366
TTD Drug ID D0S5WG
NDC Product Code 70120-095; 0187-3554; 0054-0428; 42494-339; 63629-9156; 50268-331; 63629-2148; 42794-010; 51927-4508; 60687-610; 0187-3555; 73309-270; 70120-096; 71052-466; 40032-770; 42973-193; 60687-363; 50268-332; 60687-352; 0904-6835; 43386-771; 0054-0427; 63629-2147; 59348-0016; 42794-009; 59651-331; 66639-008; 40032-771; 71666-001; 43386-770; 59651-332; 0904-6834; 63629-9157; 42494-340; 60687-599
Synonyms Flucytosine | 5-Fluorocytosine | Ancobon | Ancotil | Alcobon
Chemical Information
Molecular Formula C4H4FN3O
CAS Registry Number 2022-85-7
SMILES C1=NC(=O)NC(=C1F)N
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Anaemia01.03.02.001--
Aplastic anaemia01.03.03.002--Not Available
Asthenia08.01.01.001--Not Available
Ataxia08.01.02.004; 17.02.02.001--
Azotaemia20.01.01.001--Not Available
Blood bilirubin increased13.03.01.008--
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Cardiac arrest02.03.04.001--
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.003--Not Available
Colitis07.08.01.001--
Colitis ulcerative07.08.01.005; 10.02.01.004--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Crystalluria20.02.01.003--Not Available
Deafness04.02.01.001--Not Available
Death08.04.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Duodenal ulcer07.04.02.002--
Dyspnoea02.01.03.002; 22.02.01.004--
Enterocolitis07.08.03.003--
Eosinophilia01.02.04.001--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.009--Not Available
Gastrointestinal pain07.01.05.005--
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ADReCS-Target
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