Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Flavoxate
Drug ID BADD_D00900
Description A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Indications and Usage For symptomatic relief of dysuria, urgency, nocturia, suprapubic pain, frequency and incontinence as may occur in cystitis, prostatitis, urethritis, urethrocystitis/urethrotrigonitis.
Marketing Status approved
ATC Code G04BD02
DrugBank ID DB01148
KEGG ID D07961
MeSH ID D005422
PubChem ID 3354
TTD Drug ID D0ND2J
NDC Product Code Not Available
UNII 3E74Y80MEY
Synonyms Flavoxate | Flavoxate Hydrochloride | Hydrochloride, Flavoxate | Urispas | Uronid | Bladuril | Spasuret
Chemical Information
Molecular Formula C24H25NO4
CAS Registry Number 15301-69-6
SMILES CC1=C(OC2=C(C1=O)C=CC=C2C(=O)OCCN3CCCCC3)C4=CC=CC=C4
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state17.02.03.005; 19.13.01.001--
Dry mouth07.06.01.002--
Eosinophilia01.02.04.001--
Feeling abnormal08.01.09.014---
Headache17.14.01.001--
Hyperpyrexia08.05.02.002---
Leukopenia01.02.02.001---
Nausea07.01.07.001--
Nervousness19.06.02.003---
Palpitations02.11.04.012--
Skin disorder23.03.03.007---
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007---
Tension19.06.02.005---
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
Vision blurred06.02.06.007; 17.17.01.010--
Vomiting07.01.07.003--
Dermatosis23.03.03.017---
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene