Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fibrinogen
Drug ID BADD_D00895
Description Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. It is indicated for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
Indications and Usage For the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB09222
KEGG ID D04182
MeSH ID D005340
PubChem ID 90540
TTD Drug ID Not Available
NDC Product Code 63833-891
UNII BP8KW73WMG
Synonyms Fibrinogen | Blood Coagulation Factor I | Coagulation Factor I | Factor I, Coagulation | Factor I | gamma-Fibrinogen | gamma Fibrinogen
Chemical Information
Molecular Formula C6H14O6
CAS Registry Number 25878-23-3
SMILES C(C(C(C(C(CO)O)O)O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Bradycardia02.03.02.002---
Chills08.01.09.001; 15.05.03.016--
Dermal cyst16.26.02.001; 23.10.02.001---
Dyspnoea02.11.05.003; 22.02.01.004--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Impaired healing08.03.02.001---
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010---
Pruritus23.03.12.001--
Pulmonary embolism22.06.02.001; 24.01.06.001---
Pyrexia08.05.02.003--
Rash23.03.13.001---
Seroma08.03.05.005; 12.02.05.020--
Tachycardia02.03.02.007---
Thrombosis24.01.01.006---
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
Skin graft failure12.02.09.018; 23.07.04.019---
Embolism24.01.01.009--
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