| Pharmaceutical Information |
| Drug Name |
Exametazime |
| Drug ID |
BADD_D00860 |
| Description |
Exametazime is a diagnostic radiopharmaceutical agent commonly used for the preparation of Tc99m Exametazime injection. It acts as a chelating agent for the radioisotope technetium-99m to form a cationic complex. It is used in the detection of altered regional cerebral perfusion and for the radiolabeling of autologous leukocytes. |
| Indications and Usage |
Not Available |
| Marketing Status |
approved |
| ATC Code |
Not Available |
| DrugBank ID |
DB11179
|
| KEGG ID |
D01109
|
| MeSH ID |
C078058
|
| PubChem ID |
9552071
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
17156-023 |
| UNII |
G29272NCKL
|
| Synonyms |
exametazime | 3,3'-((2,2,-dimethyl-1,3-propanediyl)diimino)bis-2-butanone dioxime, (R*,R*-(E,E))- |
|
| Chemical Information |
| Molecular Formula |
C13H28N4O2 |
| CAS Registry Number |
105613-48-7 |
| SMILES |
CC(C(=NO)C)NCC(C)(C)CNC(C)C(=NO)C |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Blood pressure increased | 13.14.03.005 | - | - | - | | Erythema | 23.03.06.001 | - | - | - | | Face oedema | 08.01.07.003; 10.01.05.002; 23.04.01.004 | - | - | | | Pyrexia | 08.05.02.003 | - | - | | | Rash | 23.03.13.001 | - | - | - |
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