Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Feeling hot08.01.09.0090.004125%Not Available
Fibroadenoma of breast16.14.01.001; 21.05.01.005--Not Available
Fibrosis08.03.01.0010.003300%Not Available
Flatulence07.01.04.002--
Fluid retention14.05.06.002; 20.01.02.003--Not Available
Fungal infection11.03.05.001--Not Available
Furuncle11.02.05.008; 23.09.01.0040.002062%Not Available
Galactorrhoea05.03.04.002; 21.05.02.0020.005362%Not Available
Gallbladder disorder09.03.02.0010.002887%Not Available
Gastritis07.08.02.001--
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.0050.000825%
Generalised oedema08.01.07.004; 14.05.06.007--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Gestational diabetes05.06.01.008; 14.06.01.008; 18.02.04.0010.001237%Not Available
Groin pain15.03.02.0040.000825%Not Available
Haematemesis07.12.02.002; 24.07.02.011--Not Available
Haematochezia07.12.02.003; 24.07.02.012--Not Available
Haematoma24.07.01.001--
Haemoglobin13.01.05.018--Not Available
Haemoglobin decreased13.01.05.003--Not Available
Haemoptysis02.01.02.006; 22.02.03.004; 24.07.01.006--Not Available
Haemorrhagic disorder01.01.03.004; 24.07.01.0210.001237%Not Available
Haemorrhagic stroke17.08.01.011; 24.07.04.014--Not Available
Hair colour changes23.02.06.001--
Hair growth abnormal23.02.06.0060.001650%Not Available
Hallucination19.10.02.002--
Hallucination, auditory19.10.02.003--Not Available
Headache17.14.01.0010.193027%
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