Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cellulitis staphylococcal11.02.05.006; 23.09.01.0130.001650%Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.001--Not Available
Chest pain02.02.02.011; 08.01.08.002; 22.02.08.0030.037945%Not Available
Chills08.01.09.001; 15.05.03.016--
Chloasma18.08.02.002; 23.05.01.001--Not Available
Cholelithiasis09.03.01.002--Not Available
Cholestasis09.01.01.001--Not Available
Chromaturia20.02.01.002--
Cold sweat08.01.03.024; 23.02.03.002--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Crying08.01.03.005; 12.02.11.001; 17.02.05.013; 19.04.02.0020.010311%Not Available
Cyanosis02.01.02.002; 22.02.02.007; 24.03.01.007--
Cyst08.03.05.001; 16.02.02.0020.002062%Not Available
Cystitis11.01.14.001; 20.03.02.002--
Deafness04.02.01.001--Not Available
Death08.04.01.001--
Death neonatal08.04.01.002; 18.04.01.0020.000215%
Dehydration14.05.05.001--
Depressed mood19.15.02.0010.016498%Not Available
Depression19.15.01.0010.068879%
Depression suicidal19.15.01.0040.000825%Not Available
Dermatitis23.03.04.002--Not Available
Dermatitis allergic10.01.03.014; 23.03.04.0030.003300%Not Available
Diarrhoea07.02.01.001--
Diplopia06.02.06.002; 17.17.01.005--Not Available
Discomfort08.01.08.0030.066405%Not Available
Disorientation17.02.05.015; 19.13.01.002--Not Available
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