Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arthropathy15.01.01.0030.004125%Not Available
Asthenia08.01.01.001--Not Available
Asthma10.01.03.010; 22.03.01.002--Not Available
Back disorder15.03.01.0140.003300%Not Available
Back pain15.03.04.0050.069292%
Benign intracranial hypertension17.07.02.0010.000825%Not Available
Binge eating19.09.01.0010.000825%Not Available
Bleeding time prolonged13.01.02.0020.000825%Not Available
Blindness06.02.02.001; 17.17.01.003--Not Available
Blindness unilateral06.02.02.009; 17.17.01.0160.000825%Not Available
Blister12.01.06.002; 23.03.01.001--Not Available
Blood bilirubin increased13.03.01.008--
Blood cholesterol increased13.12.01.002--
Blood iron decreased13.11.01.0060.000825%Not Available
Blood oestrogen increased13.10.05.0070.000825%Not Available
Blood pressure increased13.14.03.005--Not Available
Blood prolactin increased13.10.03.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone pain15.02.01.001--
Breast cancer16.10.01.001; 21.05.01.003--Not Available
Breast discharge21.05.05.0010.004537%Not Available
Breast enlargement21.05.04.0010.003300%Not Available
Breast mass21.05.04.0020.003300%Not Available
Breast pain21.05.05.0030.023097%
Breast swelling21.05.05.0080.002062%Not Available
Breast tenderness21.05.05.0040.020623%Not Available
Burning sensation08.01.09.029; 17.02.06.0010.009899%Not Available
Carpal tunnel syndrome17.09.02.0010.001237%Not Available
Cataract06.06.01.001--
Cellulitis11.02.01.001; 23.09.01.0010.016086%Not Available
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