Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Etonogestrel
Drug ID BADD_D00852
Description Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.[A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]
Indications and Usage For use as a female contraceptive (depot).
Marketing Status Prescription; Discontinued
ATC Code G03AC08
DrugBank ID DB00294
KEGG ID D04104
MeSH ID C044815
PubChem ID 6917715
TTD Drug ID D02KIU
NDC Product Code 65089-0053; 64918-1500; 60870-0475; 78206-145; 71161-147; 63190-0480; 63190-0260; 45541-1192; 64918-1906
Synonyms etonogestrel | 13-ethyl-17-hydroxy-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one | 3-oxodesogestrel | 3-ketodesogestrel | 3-oxo desogestrel | 18,19-dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-11-methylene-, (17-alpha)- | 3-keto-desogestrel | ORG-3236 | Implanon | nexplanon
Chemical Information
Molecular Formula C22H28O2
CAS Registry Number 54048-10-1
SMILES CCC12CC(=C)C3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Polymenorrhagia21.01.03.0040.000825%Not Available
Ligament rupture12.01.07.014; 15.07.02.0080.000825%Not Available
Menstruation normal13.15.01.0450.023510%Not Available
Human chorionic gonadotropin increased13.10.05.0240.000825%Not Available
Infected dermal cyst11.01.12.024; 16.26.02.002; 23.10.02.0020.000825%Not Available
Foetal monitoring abnormal13.21.01.0070.000825%Not Available
Spinal pain08.01.08.030; 15.02.01.008; 17.10.01.0200.001237%Not Available
Invasive ductal breast carcinoma16.10.01.013; 21.05.01.0210.001650%Not Available
Body mass index abnormal13.15.01.0370.002062%Not Available
Skin texture abnormal23.03.03.0680.000825%Not Available
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