| Pharmaceutical Information |
| Drug Name |
Etidronate disodium |
| Drug ID |
BADD_D00848 |
| Description |
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.[A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid].[A203111]
Etidronic acid was granted FDA approval on 1 September 1977.[L13901] |
| Indications and Usage |
Etidronate is indicated to treat Paget's disease of bone, as well as the treatment and prevention of heterotropic ossification after total hip replacement of spinal cord injury.[L13901] |
| Marketing Status |
approved |
| ATC Code |
M05BA01 |
| DrugBank ID |
DB01077
|
| KEGG ID |
D00314
|
| MeSH ID |
D012968
|
| PubChem ID |
23894
|
| TTD Drug ID |
D00XUN
|
| NDC Product Code |
Not Available |
| UNII |
M16PXG993G
|
| Synonyms |
Etidronic Acid | (1-hydroxyethylene)diphosphonic acid | Hydroxyethylidene Diphosphonic Acid | Diphosphonic Acid, Hydroxyethylidene | Etidronate | 1-Hydroxyethane-1,1-Diphosphonate | 1 Hydroxyethane 1,1 Diphosphonate | 1-Hydroxyethylidene-1,1-Bisphosphonate | 1 Hydroxyethylidene 1,1 Bisphosphonate | EHDP | 1,1-hydroxyethylenediphosphonate | 1,1 hydroxyethylenediphosphonate | HEDP | Hydroxyethanediphosphonate | Ethanehydroxyphosphate | Ethanehydroxydiphosphonate | Etidronate Disodium | Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt | Sodium Etidronate | Etidronate, Sodium | Disodium 1-Hydroxyethylene Diphosphonate | 1-Hydroxyethylene Diphosphonate, Disodium | Diphosphonate, Disodium 1-Hydroxyethylene | Disodium 1 Hydroxyethylene Diphosphonate | Disodium Etidronate | Etidronate, Disodium | HEDSPA | Dicalcium Etidronate | Etidronate, Dicalcium | Dicalcium EHDP | EHDP, Dicalcium | Xidifon | Xydiphone | Xidiphon | Didronel | Etidronate, Tetrapotassium Salt | Salt Etidronate, Tetrapotassium | Tetrapotassium Salt Etidronate | (1-hydroxyethylene)diphosphonic acid, Tetrapotassium Salt |
|
| Chemical Information |
| Molecular Formula |
C2H6Na2O7P2 |
| CAS Registry Number |
7414-83-7 |
| SMILES |
CC(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+] |
| Chemical Structure |
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| ADRs Induced by Drug |
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