Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Estropipate
Drug ID BADD_D00836
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code Not Available
DrugBank ID Not Available
KEGG ID D00948
MeSH ID C009927
PubChem ID 5284555
TTD Drug ID D03IUY
NDC Product Code 64918-0106; 12875-9998
UNII SVI38UY019
Synonyms estropipate | piperazine estrone sulfate | estra-1,3,5(10)-trien-17-one, 3-(sulfooxy)-, compd. with piperazine (1:1) | Ogen | Harmogen | Genoral | Harmonet | Ortho-Est
Chemical Information
Molecular Formula C22H32N2O5S
CAS Registry Number 7280-37-7
SMILES CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.C1CNCCN1
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tension19.06.02.005---
Thrombophlebitis24.01.02.001---
Thrombosis24.01.01.006---
Urticaria10.01.06.001; 23.04.02.001--
Uterine leiomyoma16.04.02.001; 21.07.02.004---
Vaginal haemorrhage21.08.01.001; 24.07.03.005--
Vaginal infection11.01.10.002; 21.14.02.002--
Varicose vein24.10.04.001---
Visual impairment06.02.10.013---
Vomiting07.01.07.003--
Vulvovaginal candidiasis11.03.03.005; 21.14.02.003---
Weight decreased13.15.01.005--
Weight increased13.15.01.006--
Withdrawal bleed08.06.02.005; 21.01.01.010---
Breast discomfort21.05.05.007---
Deep vein thrombosis24.01.02.003---
Acute coronary syndrome02.02.02.015; 24.04.04.011---
Musculoskeletal discomfort15.03.04.001---
Haemorrhage24.07.01.002---
Vulvovaginal pruritus21.08.02.004; 23.03.12.009---
Embolism24.01.01.009--
Inflammation08.01.05.007; 10.02.01.089---
Porphyrin metabolism disorder03.08.01.006; 09.01.10.004; 14.14.01.006---
Corneal disorder06.08.01.004---
Retinal vascular thrombosis06.10.01.004; 24.01.07.001---
Cystitis noninfective20.03.02.001--
Vulvovaginal mycotic infection11.03.05.004; 21.14.02.004---
Abnormal withdrawal bleeding08.06.02.001; 21.01.01.008---
Intermenstrual bleeding21.01.01.015---
Superficial vein thrombosis24.01.02.016---
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