Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Estazolam
Drug ID BADD_D00819
Description A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Indications and Usage For the short-term management of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
Marketing Status approved; illicit
ATC Code N05CD04
DrugBank ID DB01215
KEGG ID D00311
MeSH ID D004949
PubChem ID 3261
TTD Drug ID D0P2CK
NDC Product Code 48087-0031; 0591-0744; 58159-096; 12828-0077; 70954-481; 70954-480; 0591-0745; 51862-074; 51862-073
UNII 36S3EQV54C
Synonyms Estazolam | Tasedan | ProSom | D-40TA | D40TA | Nuctalon
Chemical Information
Molecular Formula C16H11ClN4
CAS Registry Number 29975-16-4
SMILES C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Paraesthesia17.02.06.005; 23.03.03.094--
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Photophobia06.01.01.004; 17.17.02.006--
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Purpura01.01.04.003; 23.06.01.004; 24.07.06.005--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Rhinitis11.01.13.004; 22.07.03.006--
Seizure17.12.03.001--
Shock24.06.02.002---
Sinusitis11.01.13.005; 22.07.03.007--
Sleep disorder19.02.04.001---
Somnolence17.02.04.006; 19.02.05.003--
Stevens-Johnson syndrome10.01.01.045; 11.07.01.005; 12.03.01.014; 23.03.01.007--
Stupor17.02.04.007; 19.02.05.004---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tension19.06.02.005---
Thinking abnormal17.02.05.023; 19.10.03.001---
Thirst08.01.09.021; 14.03.02.007---
Thyroid neoplasm05.02.05.002; 16.24.01.002---
Tinnitus04.04.01.002; 17.04.07.004--
Tremor17.01.06.002--
Ulcer08.03.06.001---
Urinary hesitation20.02.02.009---
Urinary incontinence17.05.01.008; 20.02.02.010--
Urticaria10.01.06.001; 23.04.02.001--
Vaginal discharge21.08.02.002--
Vascular purpura01.01.04.007; 23.06.01.008; 24.07.06.011---
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