| Pharmaceutical Information |
| Drug Name |
Eprosartan |
| Drug ID |
BADD_D00790 |
| Description |
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced. |
| Indications and Usage |
For the management of hypertension alone or in combination with other classes of antihypertensive agents. Also used as a first-line agent in the treatment of diabetic nephropathy, as well as a second-line agent in the treatment of congestive heart failure (only in those intolerant of ACE inhibitors). |
| Marketing Status |
approved |
| ATC Code |
C09CA02 |
| DrugBank ID |
DB00876
|
| KEGG ID |
D04040
|
| MeSH ID |
C068373
|
| PubChem ID |
5281037
|
| TTD Drug ID |
D0T7US
|
| NDC Product Code |
65977-0046 |
| UNII |
2KH13Z0S0Y
|
| Synonyms |
eprosartan | 2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4- carboxyphenyl)methyl)-lH-imidazol-5-yl)methylene)-, (E)- | Teveten | SK&F 108566 | SKF-108566 |
|
| Chemical Information |
| Molecular Formula |
C23H24N2O4S |
| CAS Registry Number |
133040-01-4 |
| SMILES |
CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)C=C(CC3=CC=CS3)C(=O)O |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
|
|
|
