| Pharmaceutical Information |
| Drug Name |
Econazole nitrate |
| Drug ID |
BADD_D00741 |
| Description |
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally. |
| Indications and Usage |
For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor. |
| Marketing Status |
approved |
| ATC Code |
G01AF05; D01AC03 |
| DrugBank ID |
DB01127
|
| KEGG ID |
D00881
|
| MeSH ID |
D004464
|
| PubChem ID |
68589
|
| TTD Drug ID |
D0EV8E
|
| NDC Product Code |
63629-8646; 55545-0452; 51672-1303; 17337-0515; 23710-100; 45802-466; 63629-8645; 68788-8170; 49632-180; 51552-1316; 51927-0179; 52935-0007; 51927-0040; 63629-8647; 68788-8174 |
| UNII |
H438WYN10E
|
| Synonyms |
Econazole | Ekonazole | Gyno-Pervaryl 150 | Gyno Pervaryl 150 | Pevaryl | Econazole Nitrate | Nitrate, Econazole | Gyno-Pevaryl | Gyno Pevaryl | Gyno-Pevaril | Gyno Pevaril | GynoPevaril |
|
| Chemical Information |
| Molecular Formula |
C18H15Cl3N2O.HNO3 |
| CAS Registry Number |
24169-02-6 |
| SMILES |
C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-] |
| Chemical Structure |
|
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
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|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Erythema | 23.03.06.001 | - | - | - | | Pain | 08.01.08.004 | - | - | | | Pruritus | 23.03.12.001 | - | - | | | Rash pruritic | 23.03.13.030 | - | - | - |
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