Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Doxycycline hyclate
Drug ID BADD_D00727
Description Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline [FDA label]. This drug is a second-generation tetracycline, exhibiting lesser toxicity than first-generation tetracyclines [A174034]. Doxycycline may be used to treat a wide range of bacterial infections, depending on the results of antibiotic susceptibility testing.
Indications and Usage Not Available
Marketing Status Prescription; Discontinued
ATC Code A01AB22; J01AA02
DrugBank ID DB00254
KEGG ID D02129
MeSH ID D004318
PubChem ID 54705095
TTD Drug ID D0S0LZ
NDC Product Code 68999-984; 46708-353; 62332-387; 68308-715; 29033-053; 46708-482; 50090-2446; 68999-626; 16110-501; 70518-3135; 68308-710; 71205-156; 70518-3039; 0591-4575; 62332-362; 0395-8059; 51862-559; 63187-818; 46708-352; 53489-119; 45865-116; 68788-9037; 51862-557; 68999-625; 50090-5588; 68382-709; 70518-3363; 59929-344; 0591-6125; 0143-3142; 46708-484; 0143-9802; 24658-312; 71057-3440; 23155-141; 55700-470; 11014-0090; 71610-087; 68071-4836; 72578-054; 61919-907; 51473-0501; 38779-0434; 63629-6880; 71335-1549; 0143-2112; 62332-482; 71335-1182; 71610-117; 23155-142; 55018-151; 50090-4981; 0904-0428; 63187-845; 55488-0100; 72189-052; 62332-483; 53002-2711; 46708-388; 68308-775; 0527-1336; 0904-0430; 68071-3104; 62135-625; 10695-103; 68788-7638; 70518-3213; 60760-626; 27241-140; 50090-0023; 71335-1768; 68382-708; 46708-499; 51927-3129; 62135-984; 50268-279; 60505-4382; 71335-1316; 69434-017; 72336-596; 50090-3860; 68382-221; 60592-201; 50090-3924; 72143-211; 0591-4550; 62135-626; 23155-143; 43063-604; 72578-001; 51862-695; 63629-8262; 70518-1627; 62332-388; 70518-3214; 67296-1811; 62332-499; 51862-696; 63629-7921; 67296-0329; 0591-5553; 68071-4950; 47781-491; 60505-4384; 11014-0235; 50090-3037; 67296-1431; 0143-3141; 67296-1801; 69489-111; 43547-462; 62332-352; 55154-7128; 61919-667; 62332-353; 68071-3252; 46708-362; 16110-502; 62135-596; 50090-3859; 55289-502; 51927-0130; 51862-709; 67698-101; 68382-222; 46708-483; 16110-601; 63629-7961; 60687-513; 55154-8079; 62332-481; 50090-5560; 55289-866; 70771-1587; 42582-216; 72578-055; 63629-6371; 69434-016; 43063-019; 63629-1531; 63187-942; 27241-153; 71335-1686; 53489-647; 45865-444; 51862-562; 42806-312; 72189-127; 80425-0114; 49452-2694; 53489-120; 70934-810; 46708-387; 42806-362; 70771-1359; 63739-168; 51862-558; 68047-714; 43386-794; 67296-1743; 68071-5067; 69668-515; 68382-710; 62584-693; 70771-1104; 71205-554; 27808-234; 68071-5265; 50090-3783; 42582-215; 50090-5825; 71205-653; 63629-7178; 51862-571; 70934-625; 27241-154; 50090-3744; 50090-4867; 62991-2572; 40032-794; 43547-324; 70771-1358; 50090-5380; 68999-985; 62135-985; 68071-5259; 50268-278; 46708-363; 71205-518; 70771-1588; 51407-298; 43063-988; 27241-141; 53489-118; 70771-1589; 68308-716; 70518-1248; 46708-481; 60429-069; 23155-611; 42192-501; 29033-052; 76420-044; 68788-7474; 51552-0852; 0591-6100; 43547-325; 68071-4883; 68071-3386; 60760-215; 55289-107; 50909-8105; 50090-0026; 0069-0950; 55700-732; 62332-363; 0143-9803; 68788-7371; 67405-550; 71052-030; 68071-5232; 50090-3218; 43063-999; 62332-484; 71335-1464; 47621-018; 50268-277; 69263-501; 11014-0091
Synonyms Doxycycline | Doxycycline Monohydrate | Vibramycin | Atridox | Doxycycline Phosphate (1:1) | BMY-28689 | BMY 28689 | BMY28689 | BU-3839T | BU 3839T | BU3839T | Doryx | Doxycycline Calcium Salt (1:2) | Doxycycline Hyclate | Doxycycline Hemiethanolate | Doxycycline Monohydrochloride, 6-epimer | Doxycycline Monohydrochloride, 6 epimer | Doxycycline Monohydrochloride, Dihydrate | Doxycycline Calcium | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))- | Alpha-6-Deoxyoxytetracycline | Alpha 6 Deoxyoxytetracycline | Doxycycline-Chinoin | Doxycycline Chinoin | Hydramycin | Oracea | Periostat | Vibra-Tabs | Vibra Tabs | Vibramycin Novum | Vibravenos
Chemical Information
Molecular Formula C24H33ClN2O10
CAS Registry Number 24390-14-5
SMILES CCO.CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O.Cl
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abscess11.01.08.001--Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Angioedema10.01.05.009; 23.04.01.001--Not Available
Aphthous ulcer07.05.06.002--Not Available
Arthralgia15.01.02.001--
Back pain15.03.04.005--
Benign intracranial hypertension17.07.02.001--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bronchitis11.01.09.001; 22.07.01.001--
Condition aggravated08.01.03.004--Not Available
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Dermatitis allergic10.01.03.014; 23.03.04.003--Not Available
Dermatitis atopic10.01.04.004; 23.03.04.016--Not Available
Dermatitis exfoliative10.01.01.004; 23.03.07.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Ear infection04.03.01.006; 11.01.05.001--Not Available
Enterocolitis07.08.03.003--
Eosinophilia01.02.04.001--
Erythema23.03.06.001--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
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