Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dopamine hydrochloride
Drug ID BADD_D00709
Description One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Indications and Usage For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure
Marketing Status approved
ATC Code C01CA04
DrugBank ID DB00988
KEGG ID D00633
MeSH ID D004298
PubChem ID 65340
TTD Drug ID D0T7OW
NDC Product Code 43742-1281; 0338-1009; 0143-9252; 51662-1489; 0338-1005; 0143-9254; 0338-1007; 0404-9982; 71872-7066; 0143-9255; 0404-9981; 0409-9104; 51662-1490; 0409-5820; 65724-4500; 0143-9253; 43857-0412; 51662-1316; 43857-0279
UNII 7L3E358N9L
Synonyms Dopamine | 4-(2-Aminoethyl)-1,2-benzenediol | Hydroxytyramine | 3,4-Dihydroxyphenethylamine | 3,4 Dihydroxyphenethylamine | Dopamine Hydrochloride | Hydrochloride, Dopamine | Intropin
Chemical Information
Molecular Formula C8H12ClNO2
CAS Registry Number 62-31-7
SMILES C1=CC(=C(C=C1CCN)O)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angina pectoris02.02.02.002; 24.04.04.002--
Anxiety19.06.02.002--
Atrial fibrillation02.03.03.002--
Azotaemia20.01.01.001---
Bradycardia02.03.02.002---
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram QRS complex prolonged13.14.05.003---
Extrasystoles02.03.02.003---
Gangrene11.02.01.003; 23.06.06.001; 24.04.05.003---
Headache17.14.01.001--
Heart disease congenital02.11.01.014; 03.07.07.001---
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Palpitations02.11.04.012--
Piloerection23.02.06.005---
Tachycardia02.03.02.007---
Vasoconstriction23.06.05.007; 24.04.03.008---
Ventricular arrhythmia02.03.04.006--
Vomiting07.01.07.003--
Cardiac disorder02.11.01.003---
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