Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dopamine
Drug ID BADD_D00708
Description One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Indications and Usage For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure
Marketing Status approved
ATC Code C01CA04
DrugBank ID DB00988
KEGG ID D07870
MeSH ID D004298
PubChem ID 681
TTD Drug ID D0T7OW
NDC Product Code 55714-9002; 63083-1515
UNII VTD58H1Z2X
Synonyms Dopamine | 4-(2-Aminoethyl)-1,2-benzenediol | Hydroxytyramine | 3,4-Dihydroxyphenethylamine | 3,4 Dihydroxyphenethylamine | Dopamine Hydrochloride | Hydrochloride, Dopamine | Intropin
Chemical Information
Molecular Formula C8H11NO2
CAS Registry Number 51-61-6
SMILES C1=CC(=C(C=C1CCN)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Angina pectoris02.02.02.002; 24.04.04.002--
Anxiety19.06.02.002--
Atrial fibrillation02.03.03.002--
Azotaemia20.01.01.001---
Bradycardia02.03.02.002---
Conduction disorder02.03.01.008--
Cyanosis02.11.04.004; 22.02.02.007; 23.06.04.005; 24.03.01.007--
Dyspnoea02.11.05.003; 22.02.01.004--
Electrocardiogram QRS complex13.14.05.034---
Electrocardiogram QRS complex prolonged13.14.05.003---
Extrasystoles02.03.02.003---
Extravasation08.01.03.008---
Gangrene11.02.01.003; 23.06.06.001; 24.04.05.003---
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Necrosis08.03.03.001; 24.04.02.006---
Palpitations02.11.04.012--
Piloerection23.02.06.005---
Tachycardia02.03.02.007---
Vasoconstriction23.06.05.007; 24.04.03.008---
Ventricular arrhythmia02.03.04.006--
Vomiting07.01.07.003--
Heavy menstrual bleeding21.01.03.005---
The 1th Page    1    Total 1 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene