Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dipivefrin
Drug ID BADD_D00689
Description Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Indications and Usage Dipivefrin is a prodrug which is used as initial therapy for the control of intraocular pressure in chronic open-angle glaucoma.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB00449
KEGG ID D02349
MeSH ID C015173
PubChem ID 3105
TTD Drug ID D01JFT
NDC Product Code Not Available
UNII 8Q1PVL543G
Synonyms dipivefrin | dipivalyl epinephrine | adrenaline dipivalate | dipivaloylepinephrine | dipivefrin monophosphate, (+-)-isomer | dipivefrin perchlorate | dipivefrin propanoate, (+-)-isomer | dipivefrin tartrate (1:1), (+-)-(R-(R*,R*))-isomer | dipivefrin tartrate (1:1), (R)-(R-(R*,R*))-isomer | dipivefrin, (R)-isomer | Dipoquin | Glaucothil | Glaudrops | PMS-Dipivefrin | Propine | Diopine | ratio-Dipivefrin | Apo-Dipivefrin | d Epifrin | dipivefrin acetate, (+-)-isomer | dipivefrin citrate (1:1), (+-)-isomer | dipivefrin hydrochloride | dipivefrin hydrochloride, (+-)-isomer | dipivefrin monosulfate, (+-)-isomer | dipivefrin nitrate, (+-)-isomer
Chemical Information
Molecular Formula C19H29NO5
CAS Registry Number 52365-63-6
SMILES CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arrhythmia02.03.02.001---
Conjunctivitis06.04.01.002; 11.01.06.012--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Mydriasis06.05.03.004; 17.02.11.003---
Pain08.01.08.004--
Tachycardia02.03.02.007---
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