| Pharmaceutical Information |
| Drug Name |
Dimethicone |
| Drug ID |
BADD_D00679 |
| Description |
Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care products such as shampoo, conditioner, leave-in conditioner, and de-tangling products. On skin, it is also observed to have moisturizing actions [L1771, L1773].
A study found that that the 100 % dimethicone product is a safe and highly effective head lice treatment for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing products [L1767]. |
| Indications and Usage |
Dimethicone is a colorless liquid with both cosmetic and therapeutic uses. It is used in topical creams and ointments to help distribute the active ingredients. Dimethicone is used as an anti-foaming agent, a hair and skin conditioner, and in the treatment of head lice and, as an anti-bloating/anti-flatulence agent [L1765], [L1772]. |
| Marketing Status |
approved |
| ATC Code |
P03AX05 |
| DrugBank ID |
DB11074
|
| KEGG ID |
D01540
|
| MeSH ID |
C501844
|
| PubChem ID |
24764
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
76184-0110; 81310-010; 10888-8177; 44331-3751; 11673-087; 11822-3221; 36800-324; 36800-785; 37808-995; 49967-744; 49967-925; 53329-078; 53462-915; 58503-167; 59088-829; 59779-749; 63940-089; 64942-1305; 69968-0454; 69968-0488; 69968-0656; 69968-0766; 71358-011; 73302-203; 73302-204; 73928-101; 81310-009; 82160-351; 82301-001; 11770-2121; 11770-2125; 61301-8009; 61301-8016; 10742-7007; 36800-619; 42669-099; 43689-0024; 53329-059; 53329-060; 53329-074; 56062-619; 57337-139; 64024-619; 66977-022; 68437-013; 69968-0680; 71080-0028; 82956-0001; 61301-8005; 64487-0623; 64728-030; 10742-7002; 21130-898; 0132-8744; 37808-496; 39765-008; 53329-021; 55316-009; 0299-4114; 58503-166; 60716-070; 63148-561; 63148-563; 68437-014; 68828-704; 69842-771; 69968-0236; 69968-0441; 69968-0593; 69968-0629; 69968-0631; 69968-0762; 70557-002; 71141-619; 71574-500; 71593-101; 72288-619; 57337-037; 57337-100; 58503-107; 63736-031; 70441-0004; 71521-392; 72211-011; 73928-100; 76176-063; 10888-8152; 11770-2122; 17518-030; 20276-044; 41190-619; 49035-575; 49967-190; 53329-775; 57337-098; 58503-054; 63148-006; 68828-445; 69968-0692; 69968-0756; 71444-789; 0869-0619; 82301-004; 24385-118; 30056-006; 33992-0054; 53329-143; 53329-160; 57337-138; 59608-005; 63517-125; 63517-131; 68828-011; 68998-200; 69968-0409; 71080-0025; 71121-010; 71810-101; 10888-8173; 11770-2120; 11770-2123; 17856-1118; 33992-3035; 42669-112; 0259-2102; 53329-161; 55319-514; 57337-054; 0299-4115; 58503-114; 58503-118; 59088-333; 63148-028; 0363-2247; 63940-074; 68828-002; 68828-004; 69968-0408; 69968-0592; 72476-619; 0869-0354; 0869-0496; 64487-3640; 64728-031; 64728-033; 10742-7005; 10742-8508; 10967-675; 30142-496; 33992-0057; 41163-750; 0187-1660; 49035-496; 49967-805; 0259-2202; 59608-006; 59608-009; 62654-144; 63148-319; 68599-0204; 69968-0632; 70441-0003; 72211-010; 72288-496; 11770-2124; 64728-032; 10742-7003; 13630-0232; 0093-3204; 24385-619; 33992-0055; 41250-985; 49035-062; 50157-612; 55301-619; 57337-055; 62654-142; 68828-010; 68828-012; 69968-0679; 71080-0029; 71358-014; 76184-0100; 76184-0101; 76184-0111; 61301-8018; 10742-7006; 10742-7008; 11822-0619; 30142-619; 33992-0058; 46783-004; 49035-619; 53329-151; 53329-157; 53329-159; 58503-038; 62654-146; 63517-126; 64942-1307; 68998-201; 71141-496; 75712-496; 61301-8017; 64487-0624; 0132-0326; 53329-075; 53329-140; 53329-152; 55910-354; 57337-038; 58503-037; 58503-055; 58503-070; 58892-105; 59088-623 |
| UNII |
92RU3N3Y1O
|
| Synonyms |
dimethicone | dimeticone | dimethyl polysiloxane |
|
| Chemical Information |
| Molecular Formula |
C6H18OSi2 |
| CAS Registry Number |
107-46-0 |
| SMILES |
C[Si](C)(C)O[Si](C)(C)C |
| Chemical Structure |
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| ADRs Induced by Drug |
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