Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dichlorphenamide
Drug ID BADD_D00652
Description A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Indications and Usage For adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure
Marketing Status approved; investigational
ATC Code S01EC02
DrugBank ID DB01144
KEGG ID D00518
MeSH ID D004005
PubChem ID 3038
TTD Drug ID D0J4GO
NDC Product Code 72065-002; 59651-223; 13668-676; 71090-001; 73435-011; 72065-001; 58159-071
UNII VVJ6673MHY
Synonyms Dichlorphenamide | Dichlofenamide | Diclofenamid | Glauconide | Daranide
Chemical Information
Molecular Formula C6H6Cl2N2O4S2
CAS Registry Number 120-97-8
SMILES C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Polyuria20.02.03.0020.001430%-
Productive cough22.02.03.0050.000392%
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.0010.003251%-
Rectal haemorrhage07.12.03.001; 24.07.02.0180.000115%
Renal colic20.02.03.010--
Renal pain20.02.03.0030.000980%-
Renal tubular acidosis14.01.01.005; 20.05.03.0030.000115%-
Restlessness17.02.05.021; 19.11.02.0020.000646%
Sedation17.02.04.0050.000392%-
Skin irritation23.03.04.0090.000392%-
Skin ulcer23.07.03.003; 24.04.03.0070.000392%
Skin warm23.03.03.0140.000392%-
Sleep apnoea syndrome17.15.05.001; 19.02.05.002; 22.02.01.0130.000588%
Sleep disorder19.02.04.0010.000254%-
Somnolence17.02.04.006; 19.02.05.0030.003055%
Speech disorder17.02.08.003; 19.19.02.002; 22.12.03.0270.000703%-
Stress19.06.02.0040.000703%-
Swelling face08.01.03.100; 10.01.05.018; 23.04.01.0180.000392%-
Swollen tongue07.14.02.003; 10.01.05.015; 23.04.01.0140.000761%-
Syncope02.11.04.015; 17.02.04.008; 24.06.02.0120.000484%
Tension19.06.02.005---
Therapeutic response unexpected08.06.01.0010.000450%-
Thirst08.01.09.021; 14.03.02.0070.001176%-
Thrombocytopenia01.08.01.002---
Tinnitus04.04.01.002; 17.04.07.0040.001234%
Tremor17.01.06.0020.001176%
Trismus15.05.04.004; 17.01.03.0040.000392%
Urinary retention20.02.02.0110.000254%
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