| Drug Name |
Desirudin |
| Drug ID |
BADD_D00614 |
| Description |
Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide bridges. Desirudin has a chemical formula of C287H440N80O110S6 with a molecular weight of 6963.52.
It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.
Common side effects include: Bleeding gums, collection of blood under the skin, coughing up blood, deep, dark purple bruise and difficulty with breathing or swallowing. |
| Indications and Usage |
Indicated as prophylaxis of deep vein thrombosis for patients undergoing hip replacement surgery. |
| Marketing Status |
Prescription |
| ATC Code |
B01AE01 |
| DrugBank ID |
DB11095
|
| KEGG ID |
D03692
|
| MeSH ID |
C060225
|
| PubChem ID |
16129703
|
| TTD Drug ID |
D00UOR
|
| NDC Product Code |
Not Available |
| Synonyms |
desirudin | desulphatohirudin | recombinant HV1 hirudin | desulfatohirudin | Iprivask | IK-HIR02 | CGP 39393 | CGP-39393 | Revasc |
