Pharmaceutical Information |
Drug Name |
Denileukin diftitox |
Drug ID |
BADD_D00607 |
Description |
A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system. |
Indications and Usage |
For treatment of cutaneous T-cell lymphoma |
Marketing Status |
approved; investigational |
ATC Code |
L01XX29 |
DrugBank ID |
DB00004
|
KEGG ID |
D03682
|
MeSH ID |
C078456
|
PubChem ID |
Not Available
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TTD Drug ID |
Not Available
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NDC Product Code |
Not Available |
UNII |
25E79B5CTM
|
Synonyms |
denileukin diftitox | Ontak | LY-335348 | DAB(389)-interleukin 2 | DAB389-IL-2 | DAB(389)-IL-2 | DAB(389)IL-2 |
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Chemical Information |
Molecular Formula |
Not Available |
CAS Registry Number |
173146-27-5 |
SMILES |
Not Available |
Chemical Structure |
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ADRs Induced by Drug |
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